The purpose of this study was to increase the solubility of glipizide (gli) by solid dispersions
SDs technique with polyvinylpyrrolidone (PVP) in aqueous media. The gli–PVP solid …

The present research work was to improve the dissolution rate of glipizide which belongs to
BCS II drug by enhancing its aqueous solubility using different hydrophilic carriers like PEG …

Purpose: To develop controlled release osmotic pump tablets (COPT) of glipizide (GZ) solid
dispersion (SD). Methods: In elementary osmotic pump (EOP) tablets, an osmotic core with …

Glipizide, a poor water-soluble drug belongs to BCS class II. The proposed work aimed to
enhance the solubility of glipizide by preparing solid dispersions, using polyvinyl pyrrolidone …

Glipizide (GPZ) and GPZ-HPC solid dispersion (SD) pellets were developed and
characterized for drug release mechanisms from a multi-unit erosion matrix system for …

The aim of this study was to increase the solubility and dissolution of Glipizide in water by
solid dispersion. The solid dispersion of glipizide was prepared using water soluble carriers …

Extended release formulation of glipizide based on osmotic technology was developed and
evaluated. The effect of different formulation variables, namely, level of solubility modifier in …

The aim of the present study was to formulate a non-effervescent floating drug delivery
system of glipizide, a poorly water soluble drug. The solubility of glipizide was initially …

Poorly soluble glipizide was selected as the model drug to prepare osmotic pump tablets
(OPT) with proper accessorial material after it was made an inclusion complex by kneading …

Glimepiride (GMP) is poorly water soluble drug, so solubility is the main constraint for oral its
bioavailability. An attempt has been made to increase the solubility of this model drug by …