p53 gene mutations are common in uterine serous carcinoma and occur early in their pathogenesis.
H Tashiro, C Isacson, R Levine… - The American journal …, 1997 - ncbi.nlm.nih.gov
Uterine serous carcinoma (USC) is an uncommon but aggressive type of endometrial cancer
associated with rapid progression of disease and a poor prognosis. Both USC and its …
associated with rapid progression of disease and a poor prognosis. Both USC and its …
Early uterine serous carcinoma: clonal origin of extrauterine disease
RN Baergen, CD Warren, C Isacson… - International journal of …, 2001 - journals.lww.com
Uterine serous carcinoma (USC) is an uncommon but aggressive type of endometrial
carcinoma that is frequently associated with extrauterine disease despite minimal or no …
carcinoma that is frequently associated with extrauterine disease despite minimal or no …
Endometrial glandular dysplasia with frequent p53 gene mutation: a genetic evidence supporting its precancer nature for endometrial serous carcinoma
Abstract Purpose: Endometrial glandular dysplasia (EmGD) has been recently proposed to
be a putative precursor to endometrial serous carcinoma (ESC). The purpose of this study is …
be a putative precursor to endometrial serous carcinoma (ESC). The purpose of this study is …
Uterine papillary serous carcinoma evolves via a p53-driven pathway
UM Moll, E Chalas, M Auguste, D Meaney, J Chumas - Human pathology, 1996 - Elsevier
Uterine papillary serous carcinoma (UPSC) is a highly aggressive type of endometrial
cancer that occurs in the absence of hyperestrogenism and endometrial hyperplasia …
cancer that occurs in the absence of hyperestrogenism and endometrial hyperplasia …
p53 immunostaining as a significant adjunct diagnostic method for uterine surface carcinoma: precursor of uterine papillary serous carcinoma
W Zheng, R Khurana, S Farahmand… - The American journal …, 1998 - journals.lww.com
Uterine papillary serous carcinoma (UPSC) is a biologically aggressive carcinoma that
causes a disproportionate number of endometrial cancer deaths because of its dismal …
causes a disproportionate number of endometrial cancer deaths because of its dismal …
p53 overexpression and bcl-2 persistence in endometrial carcinoma: comparison of papillary serous and endometrioid subtypes
W Zheng, P Cao, M Zheng, EE Kramer, TA Godwin - Gynecologic oncology, 1996 - Elsevier
Forty-two cases, including 21 uterine papillary serous carcinomas (UPSC) and 21 age-,
nuclear-grade-, and clinical-stage-matched uterine endometrioid carcinomas (UEC), were …
nuclear-grade-, and clinical-stage-matched uterine endometrioid carcinomas (UEC), were …
The biological and clinical value of p53 expression in pelvic high‐grade serous carcinomas
Studies on the p53 expression and outcome for women with ovarian carcinoma have
produced conflicting results. The observed heterogeneity may be due to the range of cut‐offs …
produced conflicting results. The observed heterogeneity may be due to the range of cut‐offs …
[HTML][HTML] p53 overexpression in morphologically ambiguous endometrial carcinomas correlates with adverse clinical outcomes
K Garg, MM Leitao Jr, CA Wynveen, GL Sica, J Shia… - Modern Pathology, 2010 - Elsevier
The distinction between uterine serous and endometrioid carcinomas can usually be
achieved by morphologic examination alone. However, there are occasional …
achieved by morphologic examination alone. However, there are occasional …
[HTML][HTML] Immunohistochemical profile of endometrial adenocarcinoma: a study of 61 cases and review of the literature
S Kounelis, N Kapranos, E Kouri, D Coppola… - Modern Pathology, 2000 - Elsevier
The differences in immunohistochemical expression of p53, bcl-2, bax, estrogen receptor
(ER), and progesterone receptor (PR) were evaluated in 40 endometrioid and 21 papillary …
(ER), and progesterone receptor (PR) were evaluated in 40 endometrioid and 21 papillary …
Immunohistochemical overexpression of p16 and p53 in uterine serous carcinoma and ovarian high-grade serous carcinoma
AG Chiesa-Vottero, A Malpica… - International journal …, 2007 - journals.lww.com
The immunohistochemical expression pattern of p16 in biopsy samples has been useful as
part of a panel to distinguish adenocarcinomas arising from the endometrium from those …
part of a panel to distinguish adenocarcinomas arising from the endometrium from those …