Palytoxin induces an increase in the cation conductance of red cells.
MT Tosteson, JA Halperin, Y Kishi… - The Journal of general …, 1991 - rupress.org
Palytoxin (PTX), isolated from the marine soft coral Palythoa tuberculosa, increases the
cation conductance of human red cell membranes. In the presence of 10 (-10) M PTX and 10 …
cation conductance of human red cell membranes. In the presence of 10 (-10) M PTX and 10 …
Interaction of palytoxin with red cells: Structure-function studies
MT Tosteson, DRL Scriven, AK Bharadwaj, Y Kishi… - Toxicon, 1995 - Elsevier
Palytoxin (PTX), a potent toxin isolated from the marine soft coral Palythoa tuberculosa
increases the cationic permeability of red cell membranes and inhibits the (Na+, K+) …
increases the cationic permeability of red cell membranes and inhibits the (Na+, K+) …
Palytoxin action on the Na+, K+-ATPase and the disruption of ion equilibria in biological systems
GP Rossini, A Bigiani - Toxicon, 2011 - Elsevier
Palytoxin-group toxins (PlTX) exert their potent biological activity by altering mechanisms of
ion homeostasis in excitable and non-excitable tissues. This review will describe major …
ion homeostasis in excitable and non-excitable tissues. This review will describe major …
Mitogen‐activated protein kinases regulate palytoxin‐induced calcium influx and cytotoxicity in cultured neurons
C Vale, B Gómez‐Limia, MR Vieytes… - British journal of …, 2007 - Wiley Online Library
Background and purpose: Palytoxin (PLT) is a potent toxin that binds to the Na, K‐ATPase.
Palytoxin is highly neurotoxic and increases the cytosolic calcium concentration ([Ca2+] c) …
Palytoxin is highly neurotoxic and increases the cytosolic calcium concentration ([Ca2+] c) …
Sugar moiety of cardiac glycosides is essential for the inhibitory action on the palytoxin‐induced K+ release from red blood cells
H Ozaki, H Nagase, N Urakawa - FEBS letters, 1984 - Wiley Online Library
Palytoxin (PTX), a highly toxic and sugar‐containing substance isolated from Palythoa
tuberculosa, caused K+ release from rabbit red blood cells. Cardiac glycosides, such as …
tuberculosa, caused K+ release from rabbit red blood cells. Cardiac glycosides, such as …
Palytoxin. Recent electrophysiological and pharmacological evidence for several mechanisms of action.
C Frelin, C Van Renterghem - General pharmacology, 1995 - europepmc.org
1. Palytoxin is one of the most potent toxins known so far. It acts as an haemolysin and alters
the functioning of excitable cells. 2. A primary action of palytoxin in excitable cells is to …
the functioning of excitable cells. 2. A primary action of palytoxin in excitable cells is to …
Characterization of palytoxin-induced channels in mouse neuroblastoma cells
B Rouzaire-Dubois, JM Dubois - Toxicon, 1990 - Elsevier
Palytoxin-induced whole-cell and single channel currents were recorded in mouse
neuroblastoma cells. Palytoxin-induced single channel currents had a slope conductance of …
neuroblastoma cells. Palytoxin-induced single channel currents had a slope conductance of …
Palytoxin induces a nonselective cation channel in single ventricular cells of rat
M Ikeda, K Mitani, K Ito - Naunyn-Schmiedeberg's archives of …, 1988 - Springer
Palytoxin (PTX) causes a depolarization in every excitable tissue tested. We examined
whether PTX induces a channel current, which might be responsible for the depolarizing …
whether PTX induces a channel current, which might be responsible for the depolarizing …
Intracellular Ca2+-calmodulin system involved in the palytoxin-induced K+ release from rabbit erythrocytes
H Nagase, H Ozaki, H Karaki, N Urakawa - FEBS letters, 1986 - Elsevier
Palytoxin (PTX) caused K+ release from rabbit erythrocytes which was dependent on the
concentrations of extracellular Ca 2+ and PTX. In a Ca 2+-free solution, PTX still caused a …
concentrations of extracellular Ca 2+ and PTX. In a Ca 2+-free solution, PTX still caused a …
Characterization of the palytoxin-induced sodium conductance in frog skeletal muscle.
E Ecault, MP Sauviat - British journal of pharmacology, 1991 - ncbi.nlm.nih.gov
The effects of palytoxin (PTX) on transmembrane potentials and currents of frog skeletal
muscle were analyzed by intracellular microelectrode techniques and the double sucrose …
muscle were analyzed by intracellular microelectrode techniques and the double sucrose …