Post-ischemic inflammation is important in ischemic stroke pathology. However, details of
the inflammation process, its resolution after stroke and its effect on pathology and neural …

Injury is a key driver of inflammation, a critical yet necessary response involving several
mediators that is aimed at restoring tissue homeostasis. Inflammation in the central nervous …

Traumatic injury to the central nervous system results in the disruption of the blood
brain/spinal barrier, followed by the invasion of cells and other components of the immune …

Spinal cord injury (SCI) and spinal infarction lead to neurological complications and
eventually to paraplegia or quadriplegia. These extremely debilitating conditions are major …

Neurodegeneration, the progressive dysfunction and loss of neurons in the central nervous
system (CNS), is the major cause of cognitive and motor dysfunction. While neuronal …

Neuroinflammation is the response of the central nervous system (CNS) to disturbed
homeostasis and typifies all neurological diseases. The main reactive components of the …

Mild traumatic brain injuries (mTBI) have been associated with long-term cognitive deficits
relating to trauma-induced neurodegeneration. These long-term deficits include impaired …

Traumatic brain injury (TBI), particularly of greater severity (ie, moderate to severe), has
been identified as a risk factor for all-cause dementia and Parkinson's disease, with risk for …

Neuroinflammation is a condition characterized by the elaboration of proinflammatory
mediators within the central nervous system. Neuroinflammation has emerged as a …

Background Traumatic brain injury can trigger chronic neuroinflammation, which may
predispose to neurodegeneration. Animal models and human pathological studies …