Current perspectives on the link between neuroinflammation and neurogenesis

B Wang, K Jin - Metabolic brain disease, 2015 - Springer
The link between neuroinflammation and neurogenesis is an area of intensive research in
contemporary neuroscience. The burgeoning amount of evidence accumulated over the …

[HTML][HTML] Immune pathway activation in neurons triggers neural damage after stroke

D Wu, J Liu, J Liu, W Ge, S Wu, C Zeng, J Liang, KJ Liu… - Cell Reports, 2023 - cell.com
Ischemic brain injury is a severe medical condition with high incidences in elderly people
without effective treatment for the resulting neural damages. Using a unilateral mouse stroke …

The role of neuroinflammatory mediators in the pathogenesis of traumatic brain injury: a narrative review

Z Doganyigit, K Erbakan, E Akyuz… - ACS Chemical …, 2022 - ACS Publications
Traumatic brain injury (TBI) is a debilitating acquired neurological disorder that afflicts nearly
74 million people worldwide annually. TBI has been classified as more than just a single …

Inflammation in ischemic brain injury: timing is important

J Kriz - Critical reviews™ in Neurobiology, 2006 - dl.begellhouse.com
Inflammation is a defense reaction against diverse insults that serves to remove noxious
agents and to limit their detrimental effects. There is increasing evidence that post-ischemic …

[HTML][HTML] Neuroinflammation in traumatic brain injury: a chronic response to an acute injury

SJ Schimmel, S Acosta, D Lozano - Brain circulation, 2017 - journals.lww.com
Abstract Every year, approximately 1.4 million US citizens visit emergency rooms for
traumatic brain injuries. Formerly known as an acute injury, chronic neurodegenerative …

Priming the inflammatory pump of the CNS after traumatic brain injury

KG Witcher, DS Eiferman, JP Godbout - Trends in neurosciences, 2015 - cell.com
Traumatic brain injury (TBI) can lead to secondary neuropsychiatric problems that develop
and persist years after injury. Mounting evidence indicates that neuroinflammatory …

Innate immunity and neuroinflammation

A Shastri, DM Bonifati, U Kishore - Mediators of inflammation, 2013 - Wiley Online Library
Inflammation of central nervous system (CNS) is usually associated with trauma and
infection. Neuroinflammation occurs in close relation to trauma, infection, and …

To be or not to be (inflamed)–is that the question in anti-inflammatory drug therapy of neurodegenerative disorders?

B Marchetti, MP Abbracchio - Trends in pharmacological sciences, 2005 - cell.com
A sustained inflammatory reaction is present in acute (eg stroke) and chronic (eg
Alzheimer's disease, Parkinson's disease and multiple sclerosis) neurodegenerative …

[HTML][HTML] Inflammation in neurodegenerative disease—a double-edged sword

T Wyss-Coray, L Mucke - Neuron, 2002 - cell.com
Inflammation is a defense reaction against diverse insults, designed to remove noxious
agents and to inhibit their detrimental effects. It consists of a dazzling array of molecular and …

Systemic inflammation exacerbates behavioral and histopathological consequences of isolated traumatic brain injury in rats

A Utagawa, JS Truettner, WD Dietrich… - Experimental neurology, 2008 - Elsevier
The proinflammatory cytokine interleukin-1β (IL-1β) is induced rapidly after traumatic brain
injury (TBI) and contributes to the inflammatory events that lead to neuronal loss. Although …