Advances in research on anticancer properties of salidroside

A Sun, XL Ju - Chinese journal of integrative medicine, 2021 - Springer
Salidroside is a phenolic secondary metabolite present in plants of the genus Rhodiola, and
studies investigating its extensive pharmacological activities and mechanisms have recently …

Protective effects of salidroside on hydrogen peroxide-induced apoptosis in SH-SY5Y human neuroblastoma cells

L Zhang, H Yu, Y Sun, X Lin, B Chen, C Tan… - European journal of …, 2007 - Elsevier
Oxidative stress plays an important role in Alzheimer's disease and other neurodegenerative
disorders. Salidroside, a phenylpropanoid glycoside isolated from Rhodiola rosea L, shows …

Salidroside-mediated neuroprotection is associated with induction of early growth response genes (Egrs) across a wide therapeutic window

W Lai, Z Zheng, X Zhang, Y Wei, K Chu, J Brown… - Neurotoxicity …, 2015 - Springer
Salidroside exhibits anti-inflammatory, anti-oxidative, and anti-apoptotic properties. To
identify whether salidroside might be a candidate for treating ischemic stroke, we …

Neuroprotective effects of salidroside on focal cerebral ischemia/reperfusion injury involve the nuclear erythroid 2-related factor 2 pathway

J Han, Q Xiao, Y Lin, Z Zheng, Z He… - Neural Regeneration …, 2015 - journals.lww.com
Salidroside, the main active ingredient extracted from Rhodiola crenulata, has been shown
to be neuroprotective in ischemic cerebral injury, but the underlying mechanism for this …

Salidroside inhibited cerebral ischemia/reperfusion-induced oxidative stress and apoptosis via Nrf2/Trx1 signaling pathway

F Li, Q Mao, J Wang, X Zhang, X Lv, B Wu, T Yan… - Metabolic Brain …, 2022 - Springer
Cerebral ischemia reperfusion injury (CIRI) is still a serious problem threatening human
health. Salidroside (SAL) is a natural phenylpropanoid glycoside compound with …

Salidroside attenuates high altitude hypobaric hypoxia-induced brain injury in mice via inhibiting NF-κB/NLRP3 pathway

S Jiang, F Fan, L Yang, K Chen, Z Sun, Y Zhang… - European Journal of …, 2022 - Elsevier
Salidroside (Sal), an active ingredient from Rhodiola crenulate, has been reported to exert
neuroprotection in cerebral injury from hypobaric hypoxia (HH) at high altitude. However, it …

Salidroside inhibits inflammation through PI3K/Akt/HIF signaling after focal cerebral ischemia in rats

Y Wei, H Hong, X Zhang, W Lai, Y Wang, K Chu… - Inflammation, 2017 - Springer
Salidroside is being investigated for its therapeutic potential in stroke because it is
neuroprotective over an extended therapeutic window of time. In the present study, we …

Protective effect of salidroside on mitochondrial disturbances via reducing mitophagy and preserving mitochondrial morphology in OGD-induced neuronal injury

C Hu, Q Zhang, J Chen, B Wen, W Hang, K Xu… - Current medical …, 2021 - Springer
Salidroside is the active ingredient extracted from Rhodiola rosea, and has been reported to
show protective effects in cerebral ischemia, but the exact mechanisms of neuronal …

Pharmacological effects of salvianolic acid B against oxidative damage

Z Xiao, W Liu, Y Mu, H Zhang, X Wang… - Frontiers in …, 2020 - frontiersin.org
Salvianolic acid B (Sal B) is one of the main active ingredients of Salvia miltiorrhiza, with
strong antioxidant effects. Recent findings have shown that Sal B has anti-inflammatory, anti …

Current progress of research on neurodegenerative diseases of salvianolic acid B

R Zhao, X Liu, L Zhang, H Yang… - Oxidative Medicine and …, 2019 - Wiley Online Library
Salvia miltiorrhiza Bunge (Lamiaceae), one of the most commonly used traditional Chinese
herbs, is widely used for the treatment of cardiovascular disease, cerebrovascular disease …