Biochemical basis of the antidiabetic activity of oleanolic acid and related pentacyclic triterpenes
JM Castellano, A Guinda, T Delgado, M Rada… - Diabetes, 2013 - Am Diabetes Assoc
Oleanolic acid (OA), a natural component of many plant food and medicinal herbs, is
endowed with a wide range of pharmacological properties whose therapeutic potential has …
endowed with a wide range of pharmacological properties whose therapeutic potential has …
The molecular mechanisms underpinning the therapeutic properties of oleanolic acid, its isomer and derivatives for type 2 diabetes and associated complications
D Camer, Y Yu, A Szabo… - Molecular nutrition & food …, 2014 - Wiley Online Library
Recent research has uncovered the molecular mechanisms responsible for the therapeutic
properties of oleanolic acid (OA), its isomer ursolic acid (UA), and derivatives. In particular …
properties of oleanolic acid (OA), its isomer ursolic acid (UA), and derivatives. In particular …
Antidiabetic effect of oleanolic acid: a promising use of a traditional pharmacological agent
X Wang, YL Li, H Wu, JZ Liu, JX Hu… - Phytotherapy …, 2011 - Wiley Online Library
Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia.
Although the clear mechanisms of DM and insulin resistance are still to be cleared, it has …
Although the clear mechanisms of DM and insulin resistance are still to be cleared, it has …
[HTML][HTML] The role of triterpenes in the management of diabetes mellitus and its complications
J Nazaruk, M Borzym-Kluczyk - Phytochemistry Reviews, 2015 - Springer
Diabetes mellitus is a chronic metabolic disease which is a serious global problem. In 2010
an estimated 285 million people had diabetes and within the next 20 years this value is …
an estimated 285 million people had diabetes and within the next 20 years this value is …
Dietary triterpenes in the treatment of type 2 diabetes: To date
At present, the importance of triterpenes in food and pharmaceutical industries is mainly
based on their potential application in health food and medicine, particularly those …
based on their potential application in health food and medicine, particularly those …
[HTML][HTML] Oleanolic acid: extraction, characterization and biological activity
JM Castellano, S Ramos-Romero, JS Perona - Nutrients, 2022 - mdpi.com
Oleanolic acid, a pentacyclic triterpenoid ubiquitously present in the plant kingdom, is
receiving outstanding attention from the scientific community due to its biological activity …
receiving outstanding attention from the scientific community due to its biological activity …
[HTML][HTML] Anti-diabetic potential of plant-based pentacyclic triterpene derivatives: Progress made to improve efficacy and bioavailability
Diabetes mellitus (DM) results from the inability of the pancreas to produce sufficient insulin
or weakened cellular response to the insulin produced, which leads to hyperglycemia …
or weakened cellular response to the insulin produced, which leads to hyperglycemia …
Oleanolic, ursolic, and betulinic acids as food supplements or pharmaceutical agents for type 2 diabetes: promise or illusion?
FSG Silva, PJ Oliveira, MF Duarte - Journal of agricultural and …, 2016 - ACS Publications
Oleanolic (OA), ursolic (UA), and betulinic (BA) acids are three triterpenic acids (TAs) with
potential effects for treatment of type 2 diabetes (T2DM). Mechanistic studies showed that …
potential effects for treatment of type 2 diabetes (T2DM). Mechanistic studies showed that …
[HTML][HTML] In vitro and in vivo antidiabetic potential of monoterpenoids: An update
Diabetes mellitus (DM) is a chronic metabolic condition characterized by persistent
hyperglycemia due to insufficient insulin levels or insulin resistance. Despite the availability …
hyperglycemia due to insufficient insulin levels or insulin resistance. Despite the availability …
Oleanolic acid, a natural triterpenoid improves blood glucose tolerance in normal mice and ameliorates visceral obesity in mice fed a high-fat diet
CL de Melo, MGR Queiroz, SGC Fonseca… - Chemico-biological …, 2010 - Elsevier
Excess visceral adiposity may predispose to chronic diseases like hypertension and type 2
diabetes with a high risk for coronary artery disease. Adipose tissue secreted cytokines and …
diabetes with a high risk for coronary artery disease. Adipose tissue secreted cytokines and …
相关搜索
- antidiabetic activity oleanolic acid
- biochemical basis oleanolic acid
- antidiabetic activity biochemical basis
- therapeutic properties oleanolic acid
- natural triterpenoid oleanolic acid
- promising use oleanolic acid
- associated complications oleanolic acid
- molecular mechanisms oleanolic acid
- visceral obesity oleanolic acid
- normal mice oleanolic acid
- antidiabetic effect oleanolic acid
- biological activity oleanolic acid