Nanoparticle oral absorption and its clinical translational potential
Oral administration of pharmaceuticals is the most preferred route of administration for
patients, but it is challenging to effectively deliver active ingredients (APIs) that i) have …
patients, but it is challenging to effectively deliver active ingredients (APIs) that i) have …
[HTML][HTML] Advances in oral drug delivery
The oral route is the most common route for drug administration. It is the most preferred
route, due to its advantages, such as non-invasiveness, patient compliance and …
route, due to its advantages, such as non-invasiveness, patient compliance and …
[HTML][HTML] Role of nanostructures in improvising oral medicine
S Ghosh, S Ghosh, PC Sil - Toxicology Reports, 2019 - Elsevier
The most preferable mode of drugs administration is via the oral route but physiological
barriers such as pH, enzymatic degradation etc. limit the absolute use of this route. Herein …
barriers such as pH, enzymatic degradation etc. limit the absolute use of this route. Herein …
Recent advances in nanocarrier-based mucosal delivery of biomolecules
O Kammona, C Kiparissides - Journal of controlled release, 2012 - Elsevier
This review highlights the recent developments in the area of nanocarrier-based mucosal
delivery of therapeutic biomolecules and antigens. Macromolecular drugs have the unique …
delivery of therapeutic biomolecules and antigens. Macromolecular drugs have the unique …
Biopharmaceutical and pharmacokinetic aspects of nanocarrier-mediated oral delivery of poorly soluble drugs
Many new chemical entities have limited water solubility and therefore show low and/or
variable oral bioavailability. Among the various strategies to overcome this challenge …
variable oral bioavailability. Among the various strategies to overcome this challenge …
[HTML][HTML] Pharmacokinetic aspects of nanoparticle-in-matrix drug delivery systems for oral/buccal delivery
RC Feitosa, DC Geraldes… - Frontiers in …, 2019 - frontiersin.org
Oral route maintains its predominance among the ones used for drug delivery, especially
when medicines are self-administered. If the dosage form is solid, therapy gains in dose …
when medicines are self-administered. If the dosage form is solid, therapy gains in dose …
Oral delivery of protein-based therapeutics: gastroprotective strategies, physiological barriers and in vitro permeability prediction
The number of biological molecules emerging as therapeutics is growing exponentially due
to their higher specificity and tolerability profiles compared to small molecules. Despite this …
to their higher specificity and tolerability profiles compared to small molecules. Despite this …
The influence of nanoparticle properties on oral bioavailability of drugs
Y Wang, C Pi, X Feng, Y Hou, L Zhao… - International journal of …, 2020 - Taylor & Francis
Oral administration has been the most common therapeutic regimen in various diseases
because of its high safety, convenience, lower costs, and high compliance of patients …
because of its high safety, convenience, lower costs, and high compliance of patients …
Phytochemical delivery through nanocarriers: A review
In recent times, phytochemicals encapsulated or conjugated with nanocarriers for delivery to
the specific sites have gained considerable research interest. Phytochemicals are mostly …
the specific sites have gained considerable research interest. Phytochemicals are mostly …
Striving towards the perfect in vitro oral drug absorption model
JP Gleeson, F McCartney - Trends in pharmacological sciences, 2019 - cell.com
Oral drug delivery systems have multiple goals, assessing and enabling intestinal
absorption at efficacious doses being one of them. Here we highlight the in vitro advances in …
absorption at efficacious doses being one of them. Here we highlight the in vitro advances in …