Chronic rhinosinusitis (CRS) is related to persistent inflammation with a dysfunctional
relationship between environmental agents and the host immune system. Disturbances in …

Chronic rhinosinusitis (CRS) is a chronic inflammatory disease of the nose and sinuses that
affects up to 12% of the population in Europe and the United States. This complex disease is …

Chronic refractory sinusitis is a common feature in patients with primary immunodeficiencies.
The efficacy of standard therapeutic strategies is questionable. In an open trial we evaluated …

Chronic rhinosinusitis (CRS) significantly affects the quality of life of elderly people. 1
However, the inflammatory mechanisms of CRS in the elderly have not been well studied …

Rhinosinusitis is one of the most common health problems in the United States and affects
approximately 31 million Americans annually. 1 In adults, quality-of-life surveys have shown …

Research in immunology has brought great progress in knowledge of inflammatory
processes in the last 2 decades, which also has an impact on the upper airways. Our …

It is increasingly recognized that chronic rhinosinusitis (CRS) comprises a spectrum of
different diseases with distinct clinical presentations and pathogenic mechanisms. Defining …

Twenty patients with chronic refractory sinusitis or rhinitis were identified to have immune
defects on the basis of total immunoglobulin level, immunoglobulin G subclass, and vaccine …

Chronic rhinosinusitis (CRS) affects 12.5% of the US population. On epidemiologic grounds,
some association has been found between CRS prevalence and air pollution, active …

OBJECTIVES: The objectives of the study were to determine the prevalence of chronic
rhinosinusitis (CRS) overall and its 2 phenotypic variants, CRS with and without polyposis …