Ginseng-derived panaxadiol saponins promote hematopoiesis recovery in cyclophosphamide-induced myelosuppressive mice: potential novel treatment of …

X Sun, Y Zhao, S Qian, R Gao, L Yin, L Wang… - Chinese journal of …, 2018 - Springer
Objective To investigate the potential efficacy of panaxadiol saponins component (PDS-C), a
biologically active fraction isolated from total ginsenosides, to reverse chemotherapy …

Panaxdiol saponins component promotes hematopoiesis and modulates T lymphocyte dysregulation in aplastic anemia model mice

Z Zheng, X Yu, T Dai, L Yin, Y Zhao, M Xu… - Chinese journal of …, 2019 - Springer
Objective To investigate the potential efficacy of panaxadiol saponins component (PDS-C) in
the treatment of aplastic anemia (AA) model mice. Methods Totally 70 mice were divided into …

[HTML][HTML] Prevention effect of protopanaxadiol-type saponins saponins and protopanaxatriol-type saponins on myelosuppression mice induced by cyclophosphamide

H Zhang, L Zhang, C Yang, Y Zhang, J Li… - Frontiers in …, 2022 - frontiersin.org
Ginsenosides from ginseng are used as a therapeutic agent for various diseases. They
enhance the immunomodulatory effect in cyclophosphamide (CP)-treated tumor disease …

Research and development of the effective components of panaxdiol saponin as new Chinese patent medicine for treating hemocytopenia

R Gao, BH Chong - Chinese journal of integrative medicine, 2012 - Springer
Pancytopenia (hemocytopenia) such as pr imary immune primary thrombocytopenia (ITP),
aplastic anemia and chronic neutropenia (agnogenic leukocytopenia) were of ten t reated by …

Effects of panaxadiol saponins component as a new Chinese patent medicine on proliferation, differentiation and corresponding gene expression profile of …

W Wen, X Sun, H Zhuang, X Lin, Z Zheng… - Chinese journal of …, 2016 - Springer
Objective To investigate the effects of panaxadiol saponins component (PDS-C) isolated
from total saponins of panax ginseng on proliferation, differentiation and corresponding …

[HTML][HTML] Panaxdiol saponins component promotes hematopoiesis by regulating GATA transcription factors of intracellular signaling pathway in mouse bone marrow

TY Dai, JJ Lan, RL Gao, YN Zhao, XL Yu… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Our research team has identified a biological active component, panaxadiol
saponins component (PDS-C) isolated from total saponins of panax ginseng as a potential …

Effects of Ginseng panaxadiol saponin on proliferation and differentiation of human bone marrow CD34+ cells

GL Fang, RL Gao, XJ Lin, JM Jin - Zhongguo shi yan xue ye xue za …, 2007 - europepmc.org
The study was purposed to investigate the effects of the panaxadiol saponin (PDS) from
Ginseng on proliferation and differentiation of human CD34 (+) cells from human bone …

20 (S)‐Protopanaxdiol Suppresses the Abnormal Granule‐Monocyte Differentiation of Hematopoietic Stem Cells in 4T1 Breast Cancer‐Bearing Mouse

WQ Guo, YG Chen, RZ Shi, K He… - Evidence‐Based …, 2020 - Wiley Online Library
Panax notoginseng (PN) has been used as a qi‐and blood‐activating (Huoxue) drug for
thousands of years in China. It has also been widely used as an anticancer drug at present …

Ameliorative effects of ginsenosides on myelosuppression induced by chemotherapy or radiotherapy

M He, N Wang, W Zheng, X Cai, D Qi, Y Zhang… - Journal of …, 2021 - Elsevier
Background and ethnopharmacological relevance: As the major side effect of radiotherapy
or chemotherapy, myelosuppression usually leads to anemia, hemorrhage …

Protective effect of dammarane sapogenins against chemotherapy-induced myelosuppression in mice

Y Yang, S Xu, Q Xu, X Liu, Y Gao… - Experimental …, 2011 - journals.sagepub.com
Chemotherapy is the most common way to treat malignancies, but myelosuppression, one of
its common side-effects, is a formidable problem. The present study described the protective …