Incidence and mortality for sex-unspecific cancers are higher among men, a fact that is
largely unexplained,. Furthermore, age-related loss of chromosome Y (LOY) is frequent in …

Mosaic loss of chromosome Y (LOY) in circulating white blood cells is the most common
form of clonal mosaicism,,,–, yet our knowledge of the causes and consequences of this is …

Recent discoveries have shown that harboring cells without the Y chromosome in the
peripheral blood is associated with increased risk for all-cause mortality and disease such …

Mosaic loss of Y chromosome (mLOY) is the most frequently detected somatic copy number
alteration in leukocytes of men. In this study, we investigate blood cell counts as a potential …

The Y chromosome is frequently lost in hematopoietic cells, which represents the most
common somatic alteration in men. However, the mechanisms that regulate mosaic loss of …

Mosaic loss of the Y chromosome (mLOY) in peripheral leukocytes is a somatic event in
which a fraction of leukocytes have lost the entire Y chromosome. The frequency of mLOY …

Men have a shorter life expectancy compared with women but the underlying factor (s) are
not clear. Late-onset, sporadic Alzheimer disease (AD) is a common and lethal …

To the Editor—Recent studies have found associations between loss of chromosome Y
(LOY) in leukocytes and an increased risk for all-cause mortality1 as well as various …

Background Understanding the biological differences between sexes in cancer is essential
for personalized treatment and prevention. We hypothesized that the extreme …

Mosaic loss of chromosome Y (LOY) is the most common somatic genetic aberration and is
associated with increased risk for all-cause mortality, various forms of cancer and …