Despite the clear benefit of studying biological samples from diverse genetic backgrounds
and geographical locations, our current knowledge of disease is mostly derived from the …

Cancer therapeutics currently have the lowest clinical trial success rate of all major
diseases. Partly as a result of the paucity of successful anti-cancer drugs, cancer will soon …

As scientists working in the field of cancer biology, we often come across an innocent yet
heartrending question: When will the drug to treat cancer be invented? While understanding …

Our understanding of tumorigenesis and cancer progression as well as clinical therapies for
different cancer types have evolved dramatically in recent years. However, even with this …

The theoretical framework for the field of cancer research is based on two main principles.
The first is that cancer advances in a stepwise manner, with each alteration driving cells …

In the past 25 years, research has elucidated molecular mechanisms directing key aspects
of tumor cell behavior. Detailed understanding of these mechanisms has already changed …

Cancer research in recent years has been marked by significant developments in
understanding disease biology and foundational discoveries that have changed clinical …

Pathways to cancer therapy - Document - Gale Academic OneFile Use this link to get back to
this page. Copy Skip to Content Library Menu: Google Scholar Discovery Partner English Select …

Understanding the Cancer Biology Universe: Enigmas, Context and Future Prospects Page
1 ©2002 Landes Bioscience. Not for distribution. Donald S. Coffey *Correspondence to …

Conclusion This brief and highly selective overview glimpses a few of the conceptual and
practical advances in molecular medicine that are changing our understanding of disease …