[HTML][HTML] Pathways connecting late-life depression and dementia

C Linnemann, UE Lang - Frontiers in pharmacology, 2020 - frontiersin.org
Late-life depression is associated with significant cognitive impairment. Meta-analyses
showed that depression is associated with an increased risk for Alzheimer's disease (AD) …

Depression in Alzheimer's disease: epidemiology, mechanisms, and treatment

YY Huang, YH Gan, L Yang, W Cheng, JT Yu - Biological Psychiatry, 2023 - Elsevier
Depression and Alzheimer's disease (AD) are substantial public health concerns. In the past
decades, a link between two disease entities has received extensive acknowledgment, yet …

[HTML][HTML] Mechanisms underlying neurocognitive dysfunctions in recurrent major depression

P Gałecki, M Talarowska, G Anderson… - … medical journal of …, 2015 - ncbi.nlm.nih.gov
Recent work shows that depression is intimately associated with changes in cognitive
functioning, including memory, attention, verbal fluency, and other aspects of higher-order …

Neuropathology of depression in Alzheimer's disease: current knowledge and the potential for new treatments

AA Khundakar, AJ Thomas - Journal of Alzheimer's Disease, 2015 - content.iospress.com
Depression is among the most common behavioral and psychological symptoms of
dementia, and leads to more rapid decline and higher mortality. Treatment for depression in …

Integrated biomarkers for depression in Alzheimer's disease: A critical review

S Wenzler, C Knochel, C Balaban… - Current Alzheimer …, 2017 - ingentaconnect.com
Depression is a common neuropsychiatric manifestation among Alzheimer's disease (AD)
patients. It may compromise everyday activities and lead to a faster cognitive decline as well …

[HTML][HTML] Perspectives on the complex links between depression and dementia

A Hakim - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
This review highlights that depression is a growing health problem for the individual, and
because of its high frequency in most societies, a growing burden on health care budgets …

Neurobiological links between depression and AD: the role of TGF-β1 signaling as a new pharmacological target

F Caraci, SF Spampinato, MG Morgese… - Pharmacological …, 2018 - Elsevier
In the last several years a large number of studies have demonstrated the neurobiological
and clinical continuum between depression and Alzheimer's disease (AD). Depression is a …

Cognitive dysfunction in depression–pathophysiology and novel targets

AF Carvalho, KK Miskowiak… - CNS & Neurological …, 2014 - ingentaconnect.com
Major depressive disorder (MDD) is associated with cognitive dysfunction encompassing
several domains, including memory, executive function, processing speed and attention …

Involvement of cholinergic, adrenergic, and glutamatergic network modulation with cognitive dysfunction in Alzheimer's disease

YJ Cheng, CH Lin, HY Lane - International Journal of Molecular Sciences, 2021 - mdpi.com
Alzheimer's disease (AD), the most common cause of dementia, is a progressive
neurodegenerative disease. The number of AD cases has been rapidly growing worldwide …

Changes in hippocampal plasticity in depression and therapeutic approaches influencing these changes

W Xu, X Yao, F Zhao, H Zhao, Z Cheng… - Neural …, 2020 - Wiley Online Library
Depression is a common neurological disease that seriously affects human health. There
are many hypotheses about the pathogenesis of depression, and the most widely …