In rat thoracic aorta, 12-O-tetradecanoyl-phorbol-13-acetate (TPA) caused a slowly onset,
sustained vascular contraction. The contraction was markedly reduced in the absence of …

Intracellular calcium concentration ([Ca2+] i) was measured with aequorin in ferret and rat
aortic strips contracted with phorbol esters. In ferret aorta, 12-deoxyphorbol 13-isobutyrate …

The influence of the phorbol ester, 12-o-tetradecanoylphorbol-13 acetate (TPA) on the
contractility of rat and rabbit aorta was assessed. At 10− 8 to 10− 5 M TPA produced a …

Phorbol 12-myristate 13-acetate (PMA) induced a slow and progressive increase in tension
of rat thoracic aorta strips in the presence of extracellular Ca2+. Complete relaxation could …

The mechanism of the potentiating effect of phorbol ester on potassium-induced contraction
in rat aorta was investigated. The contractile response to KCl in the medium containing 0.5 …

To clarify the role of protein kinase C in the mechanical response, the effects of 12‐o‐
tetradecanoylphorbol‐13‐acetate (TPA), an activator of protein kinase C, were investigated …

The present study aimed to investigate the possible role of endothelium in contractile
response to phorbol 12, 13-diacetate (PDA) by measuring the contractile force in rat isolated …

Effects of sodium nitroprusside (SNP) and forskolin on the contractile responses of aortic
strips to phorbol 12-myristate 13-acetate (PMA) were investigated in the present study. PMA …

The ability of the phorbol ester tumor promoter, PDB, to activate contraction and stimulate
calcium influx was investigated in rabbit thoracic aorta. PDB caused a strong, slowly …

Phorbol esters activate protein kinase C and induce contraction in vascular smooth muscle.
The role of Ca and the sensitivity of this response to nitrovasodilators were evaluated in …