Phenotype modulation in primary cultures of arterial smooth-muscle cells: reorganization of the cytoskeleton and activation of synthetic activities
L Palmberg, M Sjölund, J Thyberg - Differentiation, 1985 - Elsevier
During primary culture, arterial smooth-muscle cells (SMCs) undergo transition from a
contractile to a synthetic phenotype. As a consequence, they lose the ability to contract and …
contractile to a synthetic phenotype. As a consequence, they lose the ability to contract and …
Functional remodeling of the contractile smooth muscle cell cortex, a provocative concept, supported by direct visualization of cortical remodeling
Simple Summary As a key element of the smooth muscle cell contractile apparatus, the actin
cytoskeleton participates in the development of force by acting as a molecular track for the …
cytoskeleton participates in the development of force by acting as a molecular track for the …
Ultrastructure of smooth muscle cells in culture
PM Motta, GR Campbell, JH Campbell - Ultrastructure of smooth muscle, 1990 - Springer
Various cell types can alter their character when the environment changes. These
alterations in character are called modulations of the differentiated state and involve …
alterations in character are called modulations of the differentiated state and involve …
Phenotype modulation in primary cultures of arterial smooth muscle cells: On the role of platelet‐derived growth factor
J Thyberg, L Palmberg, J Nilsson, T Ksiazek… - …, 1984 - Wiley Online Library
Smooth muscle cells were isolated from adult rat aorta by collagenase digestion, grown in
primary culture in the presence of 10% whole blood serum (WBS), and studied by …
primary culture in the presence of 10% whole blood serum (WBS), and studied by …
Development and differentiation of vascular smooth muscle
MW Majesky, XR Dong, J Lu - Assembly of the vasculature and its …, 2002 - Springer
After a network of large and small endothelial channels suitable to conduct the nascent
embryonic circulation has formed, the next step in vascular development is the assembly of …
embryonic circulation has formed, the next step in vascular development is the assembly of …
Regulation of differentiation of vascular smooth muscle cells
GK Owens - Physiological reviews, 1995 - journals.physiology.org
The vascular smooth muscle cell (SMC) in mature animals is a highly specialized cell whose
principal function is contraction. The fully differentiated or mature SMC proliferates at an …
principal function is contraction. The fully differentiated or mature SMC proliferates at an …
Stretch affects phenotype and proliferation of vascular smooth muscle cells
KG Birukov, VP Shirinsky, OV Stepanova… - Molecular and cellular …, 1995 - Springer
The exertion of periodic dynamic strain on the arterial wall is hypothesized to be relevant to
smooth muscle cell morphology and function. This study has investigated the effect of cyclic …
smooth muscle cell morphology and function. This study has investigated the effect of cyclic …
Connective tissue production by vascular smooth muscle in development and disease
Smooth muscle cells (SMC) play a critical role in maintaining vascular tone and in producing
and organizing connective tissue elements of the vascular wall. The vascular extracellular …
and organizing connective tissue elements of the vascular wall. The vascular extracellular …