The assembly of cytochrome c oxidase (CcO) in yeast mitochondria is shown to be
dependent on a new assembly factor designated Coa1 that associates with the …

Copper (Cu) and other transition metals are essential for living organisms but also toxic
when present in excess. To cope with this apparent paradox, organisms have developed …

Biogenesis of complex IV of the mitochondrial respiratory chain requires assembly factors for
subunit maturation, co-factor attachment and stabilization of intermediate assemblies. A …

The structural organization of the mitochondrial oxidative phosphorylation (OXPHOS)
system has received large attention in the past and most investigations led to the conclusion …

As part of the respiratory chain, c-type cytochromes are essential electron transporters. They
are characterized by the covalent attachment of a heme prosthetic group. The biogenesis of …

Three mitochondria-encoded subunits form the catalytic core of cytochrome c oxidase, the
terminal enzyme of the respiratory chain. COX1 and COX2 contain heme and copper redox …

The nuclear gene OXA1 is essential for respiratory growth in yeast. It codes for a chaperon‐
like protein, and has pleiotropic effects on the assembly of cytochrome c oxidase and ATP …

The assembly of cytochrome c oxidase (CcO) in yeast mitochondria is dependent on a new
assembly factor designated Coa2. Coa2 was identified from its ability to suppress the …

Cytochrome c oxidase (COX) assembly factor 7 (COA7) is a metazoan-specific assembly
factor, critical for the biogenesis of mitochondrial complex IV (cytochrome c oxidase) …

In most studies, amounts of protein complexes of the oxidative phosphorylation (OXPHOS)
system in different organs or tissues are quantified on the basis of isolated mitochondrial …