Twenty eight patients treated with selective serotonin reuptake inhibitors/venlafaxine were
randomized to a three-day (short) or 14-day (longer) anti—depressant taper and openly …

Objective: Prior efforts to assess the impact of antidepressant use on risk of suicide attempt
focused on antidepressant initiation or duration of use. Gaps remain in understanding risks …

Antidepressant discontinuation symptoms occur with all classes of antidepressant. A well-
described discontinuation syndrome occurs with the selective serotonin reuptake inhibitors …

To minimize the symptoms of antidepressant discontinuation, gradual tapering is necessary
for all serotonin reuptake inhibitors (SRIs) except fluoxetine, which has an extended half-life …

The value of a prospective assessment of discontinuation-emergent symptoms proximal to
the termination of antidepressant treatment cannot be overstated. Though varying in …

Background Antidepressant discontinuation symptoms are becoming an increasingly
important part of clinical practice, but the incidence of antidepressant discontinuation …

We now recognise that withdrawal symptoms from antidepressants are common, and can be
severe and long-lasting in some people. Many withdrawal symptoms overlap with symptoms …

Strong evidence supports the existence of a discontinuation syndrome following the
withdrawal of antidepressant medication, particularly second-generation antidepressants …

Abrupt interruption or cessation of selective serotonin reuptake inhibitor (SSRI) treatment
may result in discontinuation or treatment interruption symptoms. Recent reports suggested …

Demyttenaere K, Haddad P. Compliance with antidepressant therapy and antidepressant
discontinuation symptoms. Acta Psychiatr Scand 2000: 101: 50–56.© Munksgaard 2000 …