The physiologic role of smooth muscle structure in defining arterial function is poorly
understood. We aimed to elucidate the relationship between vascular smooth muscle …

Vascular smooth muscle cells in muscular arteries are more elongated than those in elastic
arteries. Previously, we reported changes in the contractility of engineered vascular smooth …

Smooth muscle cells (SMC) exhibit a functional plasticity, modulating from the mature
phenotype in which the primary function is contraction, to a less differentiated state with …

Vascular smooth muscle cells' primary function is to maintain vascular homeostasis through
active contraction and relaxation. In diseases such as hypertension and atherosclerosis, this …

Vascular smooth muscle cells (VSMCs) are the predominant cell type in the arterial wall and
normally adopt a quiescent, contractile phenotype to regulate vascular tone. In the arterial …

Early morphological and biochemical studies indicated that vascular smooth muscle cells
(VSMCs) exhibited two distinct phenotypes and that a change from the contractile to the …

Vascular smooth muscle cells can perform both contractile and synthetic functions, which
are associated with and characterised by changes in morphology, proliferation and …

This review focuses on the vascular smooth muscle cells present in the medial layer of the
blood vessels wall in the fully differentiated state (dVSMCs). The dVSMC contractile …

The molecular regulation of smooth muscle cell (SMC) behavior is reviewed, with particular
emphasis on stimuli that promote the contractile phenotype. SMCs can shift reversibly along …

Contraction of small artery (diameters typically less than 250μm) vascular smooth muscle
cells (VSMCs) plays a critical role in local control of blood flow and arterial pressure through …