Clonal hematopoiesis and risk of incident lung cancer

R Tian, B Wiley, J Liu, X Zong, B Truong… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE To prospectively examine the association between clonal hematopoiesis (CH)
and subsequent risk of lung cancer. METHODS Among 200,629 UK Biobank (UKBB) …

Clonal hematopoiesis mutations in patients with lung cancer are associated with lung cancer risk factors

W Hong, A Li, Y Liu, X Xiao, DC Christiani, RJ Hung… - Cancer research, 2022 - AACR
Clonal hematopoiesis (CH) is a phenomenon caused by expansion of white blood cells
descended from a single hematopoietic stem cell. While CH can be associated with …

Clonal hematopoiesis in late-stage non–small-cell lung cancer and its impact on targeted panel next-generation sequencing

SJ Yaung, F Fuhlbrück, M Peterson, W Zou… - JCO precision …, 2020 - ascopubs.org
PURPOSE Somatic mutations derived from the expansion of clonal populations of blood
cells (clonal hematopoiesis of indeterminate potential, or CHIP) may be detected in …

Genetics of smoking and risk of clonal hematopoiesis

MG Levin, T Nakao, SM Zekavat, S Koyama, AG Bick… - Scientific Reports, 2022 - nature.com
Clonal hematopoiesis of indeterminate potential (CHIP) and mosaic chromosomal
alterations (mCAs) represent two forms of clonal hematopoiesis where clones bearing …

Prevalence of clonal hematopoiesis mutations in tumor-only clinical genomic profiling of solid tumors

RN Ptashkin, DL Mandelker, CC Coombs… - JAMA …, 2018 - jamanetwork.com
Importance Although clonal hematopoiesis (CH) is well described in aging healthy
populations, few studies have addressed the practical clinical implications of these …

Clonal hematopoiesis and blood-cancer risk.

G Genovese, S Jaiswal, BL Ebert… - The New England …, 2015 - europepmc.org
Clonal hematopoiesis and blood-cancer risk. - Abstract - Europe PMC Sign in | Create an
account https://orcid.org Europe PMC Menu About Tools Developers Help Contact us Helpdesk …

Association of clonal hematopoiesis with chronic obstructive pulmonary disease

PG Miller, D Qiao, J Rojas-Quintero… - Blood, The Journal …, 2022 - ashpublications.org
Chronic obstructive pulmonary disease (COPD) is associated with age and smoking, but
other determinants of the disease are incompletely understood. Clonal hematopoiesis of …

Connections between clonal hematopoiesis, cardiovascular disease, and cancer: a review

O Calvillo-Argüelles, S Jaiswal, LI Shlush… - JAMA …, 2019 - jamanetwork.com
Importance Clonal hematopoiesis (CH) has been recently described as a novel driver for
cancer and cardiovascular disease (CVD). Clonal hematopoiesis is a common, age …

Therapy-related clonal hematopoiesis in patients with non-hematologic cancers is common and associated with adverse clinical outcomes

CC Coombs, A Zehir, SM Devlin, A Kishtagari, A Syed… - Cell stem cell, 2017 - cell.com
Clonal hematopoiesis (CH), as evidenced by recurrent somatic mutations in leukemia-
associated genes, commonly occurs among aging human hematopoietic stem cells. We …

Clonal hematopoiesis in survivors of childhood cancer

D Novetsky Friedman, ICC Chan… - Blood …, 2023 - ashpublications.org
Clonal hematopoiesis (CH), defined as the clonal expansion of mutated hematopoietic stem
and progenitor cells, is associated with the development of hematologic cancers …