The β-1, 4-galactosyltransferase 7 (β4GalT7) enzyme is involved in proteoglycan synthesis.
In the presence of a manganese ion, it transfers galactose from UDP-galactose to xylose on …

During the catalytic cycle of β1, 4-galactosyltransferase-1 (Gal-T1), upon the binding of
Mn2+ followed by UDP–Gal, two flexible loops, a long and a short loop, change their …

Human β1, 4-GalT (galactosyltransferase) 7 is involved in the biosynthesis of the
tetrasaccharide linker protein region (GlcAβ1→ 3Galβ1→ 3Galβ1→ 4Xylβ1)(where GlcA is …

The β1, 4-galactosyltransferase-7 (β4Gal-T7) enzyme, one of seven members of the β4Gal-T
family, transfers in the presence of manganese Gal from UDP-Gal to an acceptor sugar …

Glycosaminoglycans (GAGs) play a central role in many pathophysiological events, and
exogenous xyloside substrates of β1, 4-galactosyltransferase 7 (β4GalT7), a major enzyme …

β-1, 4-galactosyltransferase-1, a housekeeping enzyme that functions in the synthesis of
glycoconjugates, has two flexible loops, one short and one long. Upon binding a metal ion …

β‐1, 4‐galactosyltransferase 1 (β4gal‐T1, EC 2.4. 1.38) transfers galactose from UDP‐
galactose to free N‐acetyl‐d‐glucosamine or bound N‐acetyl‐d‐glucosamine‐R. Soluble …

β1, 4-Galactosyltransferase-I (β4Gal-T1) undergoes critical conformational changes upon
substrate binding from an open conformation (conf-I) to the closed conformation (conf-II) …

Six β4-galactosyltransferase (β4GalT) genes have been cloned from mammalian sources.
We show that all six genes are expressed in the Gat− 2 line of Chinese hamster ovary cells …

The crystal structure of the catalytic domain of bovine β1, 4-galactosyltransferase (Gal-T1) co-
crystallized with UDP-Gal and MnCl2 has been solved at 2.8 Å resolution. The structure not …