Context: An adequate drug dissolution behavior is essential for the therapeutic effectiveness
of all solid dosage forms. Objective: To develop a new solid self-micro-emulsifying drug …

Context: Comparative evaluation of liquid and solid self-microemulsifying drug delivery
systems (SMEDDS) as promising approaches for solubility enhancement. Objective: The …

Self-microemulsifying drug delivery systems (SMEDDS) offer potential for improving the oral
bioavailability of poorly water-soluble drugs. However, their susceptibilities during long term …

Oral route still remains the favorite route of drug administration in many diseases and till
today it is the first way investigated in the development of new dosage forms. The major …

The objective of the present study was to develop a self micro-emulsifying drug delivery
system (SMEDDS) of chlorthalidone (CTD) to improve its solubility and dissolution. CTD is a …

The aim of this work was to develop effective fast-dissolving tablet formulations of glyburide,
endowed with improved dissolution and technological properties, investigating the actual …

Background: More than 60% of the new drug molecules are lipophilic in nature. Low
aqueous solubility and thus poor bioavailability is the main issue for these drugs for …

This study aimed to develop solid self-microemulsifying drug delivery system (S-SMEDDS)
for solubility enhancement of azilsartan medoxomil (AZL). Ternary phase diagrams were …

In order to gain a better understanding of the reasons of successful self-microemulsifying
drug delivery systems (SMEDDS) formulation, ten poorly water-soluble drugs, exhibiting …

The majority of drugs have a low dissolution rate, which is a limiting step for their absorption.
In this manuscript, solid dispersions (SD), solid self-microemulsifying drug delivery systems …