First-line systemic therapy for metastatic clear-cell renal cell carcinoma: critical appraisal of emerging options
Until recently, a dichotomy existed in the front-line approach of metastatic clear-cell renal
cell carcinoma (mRCC). Specifically, patients received either targeted therapy or …
cell carcinoma (mRCC). Specifically, patients received either targeted therapy or …
First-line treatments for metastatic clear cell renal cell carcinoma: an ever-enlarging landscape
Abstract Treatment paradigm for metastatic clear cell renal cell carcinoma (mccRCC) has
changed dramatically over the recent decades. From cytokines, interleukin-2 and interferon …
changed dramatically over the recent decades. From cytokines, interleukin-2 and interferon …
Overview of current and future first-line systemic therapy for metastatic clear cell renal cell carcinoma
DM Gill, AW Hahn, P Hale, BL Maughan - Current treatment options in …, 2018 - Springer
Opinion statement Treatment of metastatic clear cell renal cancer (mccRCC) has seen
substantial progress over the last 20 years, with many regulatory approvals since 2006 …
substantial progress over the last 20 years, with many regulatory approvals since 2006 …
[HTML][HTML] Current and emerging therapies for first line treatment of metastatic clear cell renal cell carcinoma
MT Serzan, MB Atkins - Journal of cancer metastasis and treatment, 2021 - ncbi.nlm.nih.gov
The therapeutic landscape for advanced clear cell renal cell carcinoma (ccRCC) is rapidly
evolving with improved knowledge of the biology of disease leading to the incorporation of a …
evolving with improved knowledge of the biology of disease leading to the incorporation of a …
Metastatic clear-cell renal cell carcinoma in the era of immune checkpoint inhibitors: therapies and ongoing trials
TZ Zhuang, K Case, TA Olsen, JT Brown, BC Carthon… - Cancers, 2022 - mdpi.com
Simple Summary Renal cancer is within the top 10 most common malignancies worldwide,
of which clear cell histology represents the most common subtype in this cancer. Within the …
of which clear cell histology represents the most common subtype in this cancer. Within the …
[HTML][HTML] Current and emerging therapies for first-line treatment of metastatic clear cell renal cell carcinoma
MB Atkins, NM Tannir - Cancer treatment reviews, 2018 - Elsevier
There has been significant progress in the treatment of patients with advanced clear cell
renal cell carcinoma (ccRCC), with improved knowledge of disease biology and the …
renal cell carcinoma (ccRCC), with improved knowledge of disease biology and the …
Treating metastatic clear-cell renal cell carcinoma: beyond immunotherapy
G Perego, P Barzaghi, I Vavassori, F Petrelli - Medical Oncology, 2020 - Springer
First-line treatment for metastatic clear-cell renal cell carcinoma patients with intermediate
and poor-risk features consists of a combination of immune checkpoint inhibitors (eg …
and poor-risk features consists of a combination of immune checkpoint inhibitors (eg …
First-line treatment of metastatic clear cell renal cell carcinoma: what are the most appropriate combination therapies?
YA Vano, S Ladoire, R Elaidi, S Dermeche, JC Eymard… - Cancers, 2021 - mdpi.com
Simple Summary First-line treatment options for metastatic clear cell renal cell carcinoma
have significantly increased. The current recommended therapeutic strategy is based on a …
have significantly increased. The current recommended therapeutic strategy is based on a …
[HTML][HTML] The landscape of contemporary clinical trials for untreated metastatic clear cell renal cell carcinoma
Since the approval of immunotherapy checkpoint inhibitors for first-line treatment of
metastatic renal cell carcinoma, new and clinically relevant questions have emerged that …
metastatic renal cell carcinoma, new and clinically relevant questions have emerged that …
Approaches to first-line therapy for metastatic clear cell renal cell carcinoma
Abstract Purpose of Review Four immuno-oncology (IO)-based combinations have
demonstrated overall survival benefit as frontline treatment of metastatic clear cell renal cell …
demonstrated overall survival benefit as frontline treatment of metastatic clear cell renal cell …