The aim of this work was to develop effective fast-dissolving tablet formulations of glyburide,
endowed with improved dissolution and technological properties, investigating the actual …

Marketed glyburide tablets present unsatisfying dissolution profiles that give rise to variable
bioavailability. With the purpose of developing a fast-dissolving tablet formulation able to …

Context: An adequate drug dissolution behavior is essential for the therapeutic effectiveness
of all solid dosage forms. Objective: To develop a new solid self-micro-emulsifying drug …

Purpose: To develop a novel preparation approach of solid Self-Emulsifying Drug Delivery
System (s-SEDDS) based on spray congealing as potential drug delivery technology for …

Context: Comparative evaluation of liquid and solid self-microemulsifying drug delivery
systems (SMEDDS) as promising approaches for solubility enhancement. Objective: The …

Glyburide is a poorly water‐soluble oral hypoglycemic agent, with problems of variable
bioavailability and bio‐inequivalence related to its poor water‐solubility. This work …

Commercial tablets of glyburide exhibit unsatisfactory dissolution profiles and, consequently,
problems of bioinequivalence and poor bioavailability. The aim of this work was to develop …

The current research work was executed with an aim to explore and promote the potential of
self-microemusifying drug delivery systems (SMEDDS) in the form of tablets, in order to …

Oral route still remains the favorite route of drug administration in many diseases and till
today it is the first way investigated in the development of new dosage forms. The major …

Introduction. Limited aqueous solubility and subsequent poor absorption and low
bioavailability are the main challenges in oral drug delivery. Solid dispersion is a widely …