N-Acetyllactosamine is the most prevalent disaccharide moiety in the glycans on the surface
of mammalian cells and often found as repeat units in the linear and branched …

In order to understand how β-(1→ 4)-galactosyltransferase recognizes its glycosyl acceptor,
substrate specificities were investigated using synthetic 2-acetamido-2-deoxy-d …

β-1, 4-Galactosyltransferase-I (β4Gal-T1) transfers galactose from UDP-galactose to N-
acetylglucosamine (GlcNAc) residues of the branched N-linked oligosaccharide chains of …

sulfate modified N-acetylglucosamine (6-sulfo-GlcNAc) is often found as part of many
biologically important carbohydrate epitopes such as 6-sulfo-Le X. In these epitopes, the 6 …

The carbohydrate moieties found on glycoproteins have long been recognized as having
great potential to bear biologically important information. However, actual examples of …

A novel form of murine β-1, 6-N-acetylglucosaminyltransferase that forms branches in poly-N-
acetyllactosamines (designated as IGnT B) was cloned based on sequence homology to the …

Abstract α1, 3galactosyltransferase (α1, 3GalT) catalyzes the synthesis of a range of
glycoconjugates containing the Galα1, 3Gal epitope which is recognized by the naturally …

The crystal structure of the catalytic domain of bovine β1, 4-galactosyltransferase (Gal-T1) co-
crystallized with UDP-Gal and MnCl2 has been solved at 2.8 Å resolution. The structure not …

The factors regulating modifications of terminal β-Gal residues in lactosaminyl (Gaiβ→
4GlcNAcβ→ R) units in intact glycoproteins are not well understood. To examine these …

β1, 4-Galactosyltransferase I (Gal-T1) normally transfers Gal from UDP-Gal to GlcNAc in the
presence of Mn 2+ ion. In the presence of α-lactalbumin (LA), the Gal acceptor specificity is …