Ischemia‐reperfusion injury is the second most common injury of the spinal cord and has the
risk of neurological dysfunction and paralysis, which can seriously affect patient quality of …

Spinal cord injury (SCI), a fatal disease in the central nervous system, is characteristic of
weak neuronal regeneration ability and complex pathological progress. Activation of …

Spinal cord injury (SCI) is a severe neurological disease; however, few drugs have been
proved to treat SCI effectively. Neuroinflammation is the major pathogenesis of SCI …

Abstract Background Salidroside (Sal), an active component from Rhodiola crenulata, has
been confirmed to exert neuroprotective effects against hypoxia. However, its molecular …

Ethnopharmacological relevance Rhodiola crenulata is clinically used to combat hypobaric
hypoxia brain injury at high altitude with the function of invigorating Qi and promoting blood …

Salidroside (SAL) is a phenylpropanoid glycoside monomer extracted from Rhodiola at high
altitudes. It has been proven to have protective effects on myocardial injury, liver cancer …

Background Traumatic brain injury (TBI) induces a complex sequence of apopototic
cascades that contribute to secondary tissue damage. The aim of this study was to …

The spinal cord is extremely vulnerable to ischemia-reperfusion (I/R) injury, and the
mitochondrion is the most crucial interventional target. Rapamycin can promote autophagy …

Cerebral ischemia induces neuronal cell death in different ways and mitochondrial
dysfunction is an important cause. Astragaloside IV (AIV) is a natural saponin abandent in …

Background Ischemic stroke is a major global cause of death and permanent disability.
Studies have suggested that mitochondria play a critical role in maintaining cellular energy …