A major challenge for the tissue engineering is the regulation of cell behavior using
topographical cues of the artificial biomaterials without biochemical stimuli. In this study …

Material surfaces can induce cell responses such as contact guidance, yet little attention has
been paid to further cell orientation. Herein, we report an interesting phenomenon of cell …

Stem cells have a variety of applications in biological, reconstructive medicine, and tissue
engineering studies owing to their capacity to differentiate into specific cell lineages and …

Biomaterial surface modification through the introduction of defined and repeated patterns of
topography helps study cell behavior in response to defined geometrical cues. The …

Micro and nanopatterned surfaces are powerful experimental platforms for investigating the
mechanisms of cell adhesion, cell orientation, differentiation and they enable significant …

Surface topography plays an important role in cell orientation and morphogenesis. In this
study, we prepared a micropatterned surface with settling particles to obtain more detailed …

The combination of nanotechnology and stem cell biology is one of the most promising
advances in the field of regenerative medicine. This novel combination has widely been …

Anisotropic surface topography is known to induce the contact guidance of cells, and facile
and biocompatible approaches of the physical modification of the pertinent matrix surfaces …

Micro-and nano-structured substrates have been widely used in the biomedical engineering
field. Their precise control of cell morphology makes them promising for investigating …

It is well known that surface features, such as topographical or chemical cues, can affect cell
behavior from initial attachment and migration to differentiation and production of new …