Background Mosaic chromosomal alterations (mCAs) detected from blood-derived DNA are
large structural alterations of clonal haematopoietic origin and are associated with various …

Background Genetic variation has an important role in the development of non-small-cell
lung cancer (NSCLC). However, genetic factors for lung cancer have not been fully …

Introduction Mosaic loss of chromosome Y (mLOY) is the most commonly detectable mosaic
chromosomal event in cancers; however, its underlying relationship with tumorigenesis is …

Background The role of genetic background underlying the disparity of relative risk of
smoking and lung cancer between European populations and East Asians remains unclear …

Recent genome-wide association studies (GWASs) have identified common genetic variants
at 5p15. 33, 6p21–6p22 and 15q25. 1 associated with lung cancer risk. Several other …

Background. Lung cancer is the most important cause of cancer mortality worldwide, but the
underlying mechanisms of this disease are not fully understood. Copy number variations …

Genome-wide association studies (GWAS) have reported 45 single-nucleotide
polymorphisms (SNPs) that may contribute to the susceptibility of lung cancer, with the …

Background: Multiple recent genome-wide studies of single nucleotide polymorphisms
(SNP) reported associations between candidate chromosome loci and lung cancer …

Genome-wide association studies (GWAS) of lung cancer in Asian never-smoking women
have previously identified six susceptibility loci associated with lung cancer risk. To further …

To explore the impact of common variation on the risk of developing lung cancer, we
conducted a two-phase genome-wide association (GWA) study. In phase 1, we compared …