Azithromycin is a representative of azalides, a subclass of macrolide antibiotics. Chemically,
it differs from macrolides by the presence of a 15-membered lactone ring containing a …

Azithromycin is an azalide, a subclass of macrolide antibiotics. It is derived from
erythromycin, with a methyl-substituted nitrogen atom incorporated into the lactone ring, thus …

This issue of the journal contains a section on azithromycin, one of the truly new chemical
entities among antibacterial agents developed in recent decades. This antibiotic was …

Azithromycin (CAS number: 83905-01-5) was obtained by Beckman rearrangement of the
oxime derivative of the ketone of erythromycin (see Chapter 59, Erythromycin), leading to a …

OBJECTIVE: To discuss the chemistry, mechanism of action, spectrum of activity,
pharmacokinetics, clinical trials, adverse-effect profile, drug interactions, and dosage …

The azalide azithromycin, which is derived from erythromycin, contains a methyl-substituted
nitrogen in the lactone ring. This 15-membered expanded lactone ring results in improved …

One of the chemical features that distinguishes the I 5-membered ring azalide azithromycin
from the 14-membered ring macrolide compound erythromycin is the former's increased …

Synopsis The azalide antibacterial agent azithromycin is a semisynthetic acid-stable
erythromycin derivative with an expanded spectrum of activity and improved tissue …

Azithromycin contains an aza-methyl substitution in the 15-membered aglycone ring and as
such it is the prototype antibiotic of the azalide class, similar in mechanism of activity to the …

Azithromycin is an acid stable orally administered macrolide antimicrobial drug, structurally
related to erythromycin, with a similar spectrum of antimicrobial activity. Azithromycin is …