[HTML][HTML] Elucidating glial responses to products of diabetes-associated systemic dyshomeostasis
DA Padovani-Claudio, CJ Ramos, ME Capozzi… - Progress in retinal and …, 2023 - Elsevier
Diabetic retinopathy (DR) is a leading cause of blindness in working age adults. DR has non-
proliferative stages, characterized in part by retinal neuroinflammation and ischemia, and …
proliferative stages, characterized in part by retinal neuroinflammation and ischemia, and …
Emerging insights into pathogenesis
E Midena, E Pilotto - Management of Diabetic Retinopathy, 2017 - karger.com
Diabetic retinopathy (DR) is a frequent complication of diabetes mellitus (DM). Persistent
hyperglycemia leads to the activation of multiple cellular pathways involved in the …
hyperglycemia leads to the activation of multiple cellular pathways involved in the …
New insights into the pathophysiology of diabetic retinopathy: potential cell-specific therapeutic targets
Diabetic retinopathy, a leading cause of vision impairment, is classically defined by its
vascular lesions. This review examines how diabetes affects vascular cells, as well as …
vascular lesions. This review examines how diabetes affects vascular cells, as well as …
Molecular mechanisms mediating diabetic retinal neurodegeneration: potential research avenues and therapeutic targets
H Chakravarthy, V Devanathan - Journal of Molecular Neuroscience, 2018 - Springer
Diabetic retinopathy (DR) is a devastating complication of diabetes with a prevalence rate of
35%, and no effective treatment options. Since the most visible clinical features of DR are …
35%, and no effective treatment options. Since the most visible clinical features of DR are …
[HTML][HTML] Retinal cell damage in diabetic retinopathy
J Zhou, B Chen - Cells, 2023 - mdpi.com
Diabetic retinopathy (DR), the most common microvascular complication that occurs in
diabetes mellitus (DM), is the leading cause of vision loss in working-age adults. The …
diabetes mellitus (DM), is the leading cause of vision loss in working-age adults. The …
[HTML][HTML] The importance of glial cells in the homeostasis of the retinal microenvironment and their pivotal role in the course of diabetic retinopathy
FS Sorrentino, M Allkabes, G Salsini, C Bonifazzi… - Life sciences, 2016 - Elsevier
Diabetic retinopathy (DR) is a remarkable microvascular complication of diabetes and it has
been considered the leading cause of legal blindness in working-age adults in the world …
been considered the leading cause of legal blindness in working-age adults in the world …
[HTML][HTML] Mechanistic insights into pathological changes in the diabetic retina: implications for targeting diabetic retinopathy
Increasing evidence points to inflammation as one of the key players in diabetes-mediating
adverse effects to the neuronal and vascular components of the retina. Sustained …
adverse effects to the neuronal and vascular components of the retina. Sustained …
[HTML][HTML] Early Neural Changes as Underlying Pathophysiological Mechanism in Diabetic Retinopathy
A Cantó, J Martínez, G Perini-Villanueva… - International Journal of …, 2021 - mdpi.com
Diabetes mellitus is a chronic disease often accompanied by diabetic retinopathy (DR), one
of the most common diabetic complications. DR is an eye condition that causes vision …
of the most common diabetic complications. DR is an eye condition that causes vision …
Targeted pharmacotherapy against neurodegeneration and neuroinflammation in early diabetic retinopathy
KD Rolev, X Shu, Y Ying - Neuropharmacology, 2021 - Elsevier
Diabetic retinopathy (DR), the most frequent complication of diabetes, is one of the leading
causes of irreversible blindness in working-age adults and has traditionally been regarded …
causes of irreversible blindness in working-age adults and has traditionally been regarded …
Neurodegeneration in the pathogenesis of diabetic retinopathy: molecular mechanisms and therapeutic implications
MS Stem, TW Gardner - Current medicinal chemistry, 2013 - ingentaconnect.com
Diabetic retinopathy (DR), commonly classified as a microvascular complication of diabetes,
is now recognized as a neurovascular complication or sensory neuropathy resulting from …
is now recognized as a neurovascular complication or sensory neuropathy resulting from …