Glycosyltransferase-catalyzed synthesis of non-natural oligosaccharides
R Öhrlein - Biocatalysis-From Discovery to Application, 1999 - Springer
Enzymes are indispensable tools in modern organic synthesis. Recent progress in cloning
techniques, microbiology and protein purification supply an ever growing number and …
techniques, microbiology and protein purification supply an ever growing number and …
Recent advances in the oligosaccharide synthesis promoted by catalytically engineered glycosidases
G Perugino, B Cobucci‐Ponzano… - Advanced Synthesis …, 2005 - Wiley Online Library
In oligosaccharide synthesis the chemo‐enzymatic approach is often chosen to obtain the
desired glycosidic bond by exploiting the exquisite substrate specificity and stereoselectivity …
desired glycosidic bond by exploiting the exquisite substrate specificity and stereoselectivity …
Oligosaccharide synthesis by glycosynthases
Oligosaccharide synthesis is becoming increasingly important to the pharmaceutical
industry because these biomolecules have potential application as therapeutics. Enzymatic …
industry because these biomolecules have potential application as therapeutics. Enzymatic …
Glycosynthases: new enzymes for oligosaccharide synthesis
M Moracci, A Trincone, M Rossi - Journal of Molecular Catalysis B …, 2001 - Elsevier
The mutation of putative acid/base and nucleophile of the active sites of retaining glycosyl
hydrolases, together with kinetic analysis of the mutants, and stereochemical identification of …
hydrolases, together with kinetic analysis of the mutants, and stereochemical identification of …
Glycosynthases in biocatalysis
B Cobucci‐Ponzano, A Strazzulli… - Advanced Synthesis …, 2011 - Wiley Online Library
Glycosynthases, engineered glycoside hydrolases that are able to synthesize glycans in
quantitative yields without hydrolyzing them, are among the most interesting tools for the …
quantitative yields without hydrolyzing them, are among the most interesting tools for the …
[HTML][HTML] Synthesis of glycosides by glycosynthases
MR Hayes, J Pietruszka - Molecules, 2017 - mdpi.com
The many advances in glycoscience have more and more brought to light the crucial role of
glycosides and glycoconjugates in biological processes. Their major influence on the …
glycosides and glycoconjugates in biological processes. Their major influence on the …
Chemical transformations employing glycosyltransferases
U Gambert, J Thiem - Glycoscience Synthesis of Oligosaccharides and …, 2008 - Springer
Abstract Early on, Emil Fischer proposed the use and technological application of enzymes
in natural product chemistry, in particular in peptide and carbohydrate synthesis. After …
in natural product chemistry, in particular in peptide and carbohydrate synthesis. After …
Glycosidases and glycosynthases in enzymatic synthesis of oligosaccharides: an overview
APS Planas, M Faijes - Afinidad. Vol. 59, n. 500 (2002), p. 295-313, 2002 - dau.url.edu
Retaining glycosidases have been extensively studied for the synthesis of oligosaccharides
and glycoconjugates as a convenient enzymatic approach to achieve the required regio-and …
and glycoconjugates as a convenient enzymatic approach to achieve the required regio-and …
Glycosyltransferases as biocatalysts
MM Palcic - Current opinion in chemical biology, 2011 - Elsevier
Glycosyltransferases are useful synthetic tools for the preparation of natural
oligosaccharides, glycoconjugates and their analogues. High expression levels of …
oligosaccharides, glycoconjugates and their analogues. High expression levels of …
Recent developments in the use of enzymes in oligo-and polysaccharide synthesis
S Shoda, S Kobayashi - Trends in Polymer Science, 1997 - infona.pl
Oligo-and polysaccharides are important macromolecules in living systems, showing their
multifunctional characteristics in the construction of cell walls, energy storage, cell …
multifunctional characteristics in the construction of cell walls, energy storage, cell …