Cyclodextrins are oligosaccharides which form a new group of pharmaceutical excipients.
Cyclodextrins have been added to aqueous eye drop preparations to solubilize lipophilic …

Most ocular diseases are treated by topical drug application in the form of aqueous eye drop
solutions. Recent studies have shown that cyclodextrins are useful additives in ophthalmic …

Cyclodextrins are cylindrical oligosaccharides with a lipophilic central cavity and hydrophilic
outer surface. They can form water‐soluble complexes with lipophilic drugs, which 'hide'in …

Ideally, eye drop formulations are aqueous solutions. Many drugs that are useful in topical
application to the eye are not sufficiently water soluble to be dissolved in simple aqueous …

Cyclodextrins are cyclic oligosaccharides that are able to form water-soluble complexes with
many lipophilic drugs. Thus, through cyclodextrin complexation it is possible to formulate …

It is generally believed that it is virtually impossible to obtain therapeutic drug concentrations
in the posterior segment of the eye after topical application of aqueous, low viscosity eye …

In this paper the possible applications of cyclodextrins in ophthalmic preparations are
reviewed. First, an overview is given of the benefical effects of cyclodextrins, including an …

Cyclodextrins are oligosaccharides having outer hydrophilic surface and central
hydrophobic cavity. These agents form inclusion complexes with poorly water-soluble drugs; …

Beta-cyclodextrins are cyclic molecules with a hydrophilic outer side and a central
hydrophobic cavity. Through the inclusion of drug molecules into their cavities, ie the …

PURPOSE: To test an aqueous eye drop solution containing a high concentration of
dexamethasone in a cyclodextrin-based drug delivery system. This system increases both …