Solidification to improve the biopharmaceutical performance of SEDDS: Opportunities and challenges

P Joyce, TJ Dening, TR Meola, HB Schultz… - Advanced drug delivery …, 2019 - Elsevier
Self-emulsifying drug delivery systems (SEDDS) offer potential for overcoming the inherent
slow dissolution and poor oral absorption of hydrophobic drugs by retaining them in a …

Self-micro emulsifying drug delivery systems (SMEDDS): a review on physico-chemical and biopharmaceutical aspects

SD Maurya, RKK Arya, G Rajpal… - Journal of Drug Delivery …, 2017 - jddtonline.info
Nearly 40% of new drug candidates exhibit low solubility in water, which is a challenge in
development of optimum oral solid dosage form in terms of formulation design and …

[PDF][PDF] Development of solid SEDDS, III: Application of Acconon® C-50 and Gelucire® 50/13 as both solidifying and emulsifying agents for medium chain triglycerides

N Patel, DM Dalrymple… - International Journal of …, 2016 - jefc.scholasticahq.com
Solid self-emulsifying drug delivery systems (SEDDS) for medium chain triglycerides
(Captex® 355, ABITEC) were developed using stearoyl polyoxyl glycerides (Acconon® C …

[PDF][PDF] Novel approaches for solidification of SMEDDS

SG Talele, VR Gudsoorkar, M Pharmacy - Int J Pharm Biosci, 2016 - jpbs-online.com
SMEDDS are isotropic mixtures of drug, oil, surfactant and co-surfactant that have unique
ability of forming fine o/w micro-emulsion upon mild agitation followed by dilution in aqueous …

[PDF][PDF] Solubility of ocular therapeutic agents in self-emulsifying oils. I. Self-emulsifying oils for ocular drug delivery: Solubility of indomethacin, aciclovir and …

A Czajkowska-Kosnik, M Sznitowska - Acta Pol Pharm, 2009 - ptfarm.pl
Self-emulsifying drug delivery systems (SEDDS) were prepared by dissolving Cremophor
EL, Tween 20, Tween 80 and Span 80 (1% or 5%) in oils (Miglyol 812 or castor oil) …

[PDF][PDF] Development and in vitro evaluation of polar lipid based lipospheres for oral delivery of peptide drugs

MR Singh, D Singh, S Saraf - Int J Drug Deliv, 2009 - academia.edu
A 3 2 factorial design was employed to produce oral sustained release lipospheres
prepared by modified double emulsion solvent evaporation technique for Serratiopeptidase …