Cyclodextrins in drug delivery
T Loftsson, P Jarho, M Másson… - Expert opinion on drug …, 2005 - Taylor & Francis
Cyclodextrins are a family of cyclic oligosaccharides with a hydrophilic outer surface and a
lipophilic central cavity. Cyclodextrin molecules are relatively large with a number of …
lipophilic central cavity. Cyclodextrin molecules are relatively large with a number of …
Cyclodextrins: their future in drug formulation and delivery
VJ Stella, RA Rajewski - Pharmaceutical research, 1997 - Springer
Since their discovery, cyclodextrins and their ability to form inclusion complexes have
fascinated chemists, formulators and recently, entrepreneurs. This mini-review has as its …
fascinated chemists, formulators and recently, entrepreneurs. This mini-review has as its …
Cyclodextrins in delivery systems: Applications
Cyclodextrins (CDs) are a family of cyclic oligosaccharides with a hydrophilic outer surface
and a lipophilic central cavity. CD molecules are relatively large with a number of hydrogen …
and a lipophilic central cavity. CD molecules are relatively large with a number of hydrogen …
Cyclodextrins for drug delivery
AL Laza-Knoerr, R Gref, P Couvreur - Journal of drug targeting, 2010 - Taylor & Francis
Cyclodextrins (CDs) are macrocyclic oligosaccharides composed of α (1, 4)-linked
glucopyranose subunits. These molecules possess a cage-like supramolecular structure …
glucopyranose subunits. These molecules possess a cage-like supramolecular structure …
Cyclodextrins in parenteral formulations
T Loftsson - Journal of Pharmaceutical Sciences, 2021 - Elsevier
Most drugs have very limited solubility in water and some can be extremely difficult to
formulate as parenteral solutions where the dose should preferably be dissolved in couple …
formulate as parenteral solutions where the dose should preferably be dissolved in couple …
Role of cyclodextrins in improving oral drug delivery
T Loftsson, ME Brewster, M Masson - American Journal of Drug Delivery, 2004 - Springer
The use of high-throughput screening and similar techniques in drug discovery has put a
number of evolutionary pressures on drug candidates such that over time there is a …
number of evolutionary pressures on drug candidates such that over time there is a …
Cyclodextrins as drug carrier molecule: a review
A Rasheed - Scientia Pharmaceutica, 2008 - mdpi.com
The cyclodextrins have a wide range of applications in different areas of drug delivery and
pharmaceutical industry due to their complexation ability and other versatile characteristics …
pharmaceutical industry due to their complexation ability and other versatile characteristics …
Cyclodextrins in topical drug formulations: theory and practice
T Loftsson, M Masson - International journal of pharmaceutics, 2001 - Elsevier
Cyclodextrins are cyclic oligosaccharides with a hydrophilic outer surface and a somewhat
lipophilic central cavity. Cyclodextrins are able to form water-soluble inclusion complexes …
lipophilic central cavity. Cyclodextrins are able to form water-soluble inclusion complexes …
Solubility enhancement and application of cyclodextrins in local drug delivery
DH Kim, SE Lee, YC Pyo, P Tran, JS Park - Journal of Pharmaceutical …, 2020 - Springer
Cyclodextrins (CDs) have been used in many pharmaceutical formulations as their
constitution and inherent shape present advantages for drugs with poor aqueous solubility …
constitution and inherent shape present advantages for drugs with poor aqueous solubility …
Cyclodextrins in drug delivery systems and their effects on biological barriers
Á Haimhoffer, Á Rusznyák, K Réti-Nagy… - Scientia …, 2019 - mdpi.com
Cyclodextrins are widely used excipients, composed of glucopyranose units with a cyclic
structure. One of their most important properties, is that their inner cavity is hydrophobic …
structure. One of their most important properties, is that their inner cavity is hydrophobic …