Defects of antibody production are the most common of the primary immune defects of man.
While these defects have been described in clinical terms for more than five decades, in …

The sinopulmonary tract is the major site of infection in patients with primary antibody
deficiency syndromes, and structural lung damage arising from repeated sepsis is a major …

NOVEMBER 1999 bronchi,” 15 although we now recognize that repair and resolution can
occur. The definition is frequently extended to smaller airways as well. The process is …

To the Editor, In the majority of primary antibody deficiency (PAD) patients receiving IgG
replacement therapy (IgGRT), the risk of serious infections is reduced; however, a significant …

Primary immunodeficiences (ID), once considered to be very rare, are now increasingly
recognized thanks to more knowledge in the immunological field and to the availability of …

Primary antibody deficiency (PAD) is the most commonly diagnosed inborn error of
immunity, consisting of numerous conditions in which impairment of immunoglobulin …

Bronchiectasis, the presence of bronchial wall thickening with airway dilatation, is a
particularly challenging complication of primary antibody deficiencies. While susceptibility to …

A 5-years multicenter prospective study on 201 patients with common variable
immunodeficiencies and 101 patients with X-linked agammaglobulinemia over a cumulative …

Primary antibody deficiencies (PADs) are the most common form of primary
immunodeficiency and predispose to severe and recurrent pulmonary infections, which can …

Immunoglobulin therapy is the administration of human polyvalent IgG and represents the
most effective treatment to prevent recurrent infections in antibody deficiency patients …