[HTML][HTML] Xiaoyaosan slows cancer progression and ameliorates gut dysbiosis in mice with chronic restraint stress and colorectal cancer xenografts

Z Zhang, S Shao, Y Zhang, R Jia, X Hu, H Liu… - Biomedicine & …, 2020 - Elsevier
Depression is a risk factor for colorectal cancer (CRC) progression. Xiaoyaosan (XYS) is a
traditional Chinese medicine prescription for treating depression. Our present study aimed to …

Xiaoyaosan, a traditional Chinese medicine, inhibits the chronic restraint stress-induced liver metastasis of colon cancer in vivo

L Zhao, X Zhu, Y Ni, J You, A Li - Pharmaceutical Biology, 2020 - Taylor & Francis
Context Xiaoyaosan (XYS), a traditional Chinese medicine (TCM), has been widely used to
relieve a variety of disorders caused by depression. Objective This study evaluates the effect …

Effect of Xiaoyaosan on colon morphology and intestinal permeability in rats with chronic unpredictable mild stress

F Ding, J Wu, C Liu, Q Bian, W Qiu, Q Ma, X Li… - Frontiers in …, 2020 - frontiersin.org
Purpose In our present study, a rat depression model induced by 6 weeks of chronic
unpredictable mild stress (CUMS) was established, and we investigated how Xiaoyaosan …

[HTML][HTML] Xiaoyaosan improves depressive-like behavior in rats with chronic immobilization stress through modulation of the gut microbiota

HZ Zhu, YD Liang, QY Ma, WZ Hao, XJ Li… - Biomedicine & …, 2019 - Elsevier
Depression has become the leading cause of disability worldwide and a growing public
health problem in China. In addition, intestinal flora may be associated with depression. This …

Tong-Xie-Yao-Fang promotes dendritic cells maturation and retards tumor growth in colorectal cancer mice with chronic restraint stress

Y Jiang, Y Hu, Y Yang, R Yan, L Zheng, X Fu… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Depression is one of the important risk factors that
accelerate the progression of colorectal cancer (CRC). Tong-Xie-Yao-Fang (TXYF) is a …

[HTML][HTML] Xiao-Chai-Hu-Tang ameliorates tumor growth in cancer comorbid depressive symptoms via modulating gut microbiota-mediated TLR4/MyD88/NF-κB …

S Shao, R Jia, L Zhao, Y Zhang, Y Guan, H Wen, J Liu… - Phytomedicine, 2021 - Elsevier
Background Depressive symptoms are thought to promote cancer development and
depressive remission has been reported to be effective for defeating cancer. The herbal …

Xiaoyaosan improves antibiotic-induced depressive-like and anxiety-like behavior in mice through modulating the gut microbiota and regulating the NLRP3 …

W Hao, J Wu, N Yuan, L Gong, J Huang… - Frontiers in …, 2021 - frontiersin.org
Disturbance of the gut microbiota plays an essential role in mental disorders such as
depression and anxiety. Xiaoyaosan, a traditional Chinese medicine formula, has a wide …

[HTML][HTML] Banxia Xiexin decoction, a traditional Chinese medicine, alleviates colon cancer in nude mice

S Yan, Y Yue, J Wang, W Li, M Sun… - Annals of translational …, 2019 - ncbi.nlm.nih.gov
Methods Fifty SPF BALB/c nude mice were selected to establish an animal model of colon
cancer bearing nude mice. Establishment of nude mice intestinal cancer model by …

Xiaoyaosan exerts therapeutic effects on the colon of chronic restraint stress model rats via the regulation of immunoinflammatory activation induced by the TLR4 …

HZ Zhu, YD Liang, WZ Hao, QY Ma… - Evidence‐Based …, 2021 - Wiley Online Library
Depression is the neurological manifestation most commonly associated with
gastrointestinal diseases. The release of inflammatory cytokines mediated by TLR4/NLRP3 …

Anti-depressive effects of Xiaoyaosan, Shugan and Jianpi herbal treatments: role on the gut microbiome of CUMS rats

X Liu, M Lv, Y Wang, P Qu, S Li, Z Yu, X Qin - Phytomedicine, 2021 - Elsevier
Background Xiaoyaosan (XYS), a classic traditional Chinese medicine (TCM) prescription
that contained eight Chinese herbs, has been used for treating depression for thousands of …