Endogenous polyamines mediate acute metabolic effects and cardiac hypertrophy
associated to β-adrenoceptor stimulation. The aim of this study is to characterize the role of …

Antihypertensive and cardioprotective effects of angiotensin I-converting enzyme (ACE)
inhibitors are well established and have usually been attributed to the inhibition of …

Ornithine decarboxylase activity was higher in the left ventricle than in the right ventricle of
the rat. Swimming exercise for 2 hours caused an increase in left ventricular but not right …

We investigated whether selective β1-adrenoceptor stimulation causes hypertrophic growth
on isolated ventricular cardiomyocytes from adult rat. As parameters for the induction of …

ABSTRACT Omithine decarboxylase(ODC; EC 4.1. 1.17) is an important enzyme in the
synthesis of polyamines and is assoaated with growth and differentiation. Insulin stimulation …

Polyamines contribute to several physiological and pathological processes, including
cardiac hypertrophy in experimental animals. This involves an increase in ornithine …

Treatment with thyroxine for 7 days to produce myocardial hypertrophy led to an increase in
the content of putrescine, spermidine, and spermine in the rat heart. The content of …

Imidazoline receptors are divided into I1 and I2 subtypes. I1-imidazoline receptors are
distributed in the heart and are upregulated during hypertension or heart failure. The aim of …

Recent studies have shown that aldosterone may play a critical role in the transition to heart
failure and that heart is a direct target of the action of aldosterone, which can provoke …

Intraperitoneal injection of deionized water (0.25 ml/10 g body wt) produced a large increase
in ornithine decarboxylase activity in cerebral cortex and heart of 6 day old rats, but had no …