This review gives an overview of clinical characteristics, treatment and outcome of nutritional
and acquired cobalamin (Cbl; synonym: vitamin B12) deficiencies, inborn errors of Cbl …

Deficiency of either folic acid or vitamin B12 results in megaloblastic anaemia: the release
into the circulation of immature erythrocytes due to a failure of the normal process of …

Adenyl cobamide (commonly known as pseudovitamin B12) is synthesized by intestinal
bacteria or ingested from edible cyanobacteria. The effect of pseudovitamin B12 on the …

There are 2 currently known enzymes in humans that utilize vitamin B-12 as a cofactor—
namely, cytoplasmic methionine synthase and mitochondrial methylmalonyl-CoA mutase …

We have studied the intracellular binding of radioactive cobalamin by normal cultured
human fibroblasts grown in medium containing [57Co]-cobalamin. We have also assessed …

This review focusses on research performed by the author and coworkers. The absorption,
turnover and excretion of cobalamin and the pathogenesis of cobalamin deficiency states …

Dialyzed extracts from human bone marrow catalyze [5-14 C] methyltetrahydrofolate
homocysteine transmethylation at slow but significant rates which can be detected by using …

Many coenzymes are vitamins that are assimilated in mammals into their active form from
precursors obtained from the diet. They are often both rare and reactive rendering the …

Humans, as well as other mammals, must convert ingested vitamin B 12 to active coenzyme
forms for biologic activity. We found that human fibroblasts in tissue culture are capable of …

A 7-year-old child has been studied, who had an error of vitamin B 12 metabolism leading to
intracellular deficiency of cobalamins, including the two coenzyme forms, methyl-and …