The challenges in medical management of cobalamin deficiency lie in attention to the
unique pathophysiology that underlies cobalamin deficiency, more than in the mechanics of …

Purpose: Vitamin B12 deficiency is a cause of preventable growth and developmental
retardation in children. In this respect, alternative methods such as oral and sublingual …

Whereas low cobalamin levels have been studied intensively, systematic information about
high levels, especially in the clinical setting, is scarce. Therefore, a prospective comparison …

BACKGROUND: High dose oral cobalamin therapy was shown to be effective for pernicious
anemia and other cobalamin deficiency states 30 years ago, and physicians and patients …

Vitamin B12 deficiency causes a wide range of hematological, gastrointestinal, psychiatric
and neurological disorders. Hematological presentation of cobalamin deficiency ranges …

Cobalamin levels are frequently requested in geriatric practice. The focus is usually on
detecting B12 deficiency, as shown by an extensive literature (1-4). In contrast, little is known …

Introduction Although consensus guidelines recommend checking serum B12 in patients
with dementia, clinicians are often faced with various questions:(1) Which patients should be …

Vitamin B 12 deficiency is a common condition which can present with non-specific clinical
features, and in severe cases with neurological or haematological abnormalities. Although …

Results: When no oxidant risks were present, older subjects (⩾ 70 years) had higher
metabolite values than younger individuals (< 70 years). MMA values were even higher in …

Purpose The high incidence of cobalamin (vitamin B12) deficiency results in frequent
dosages of this vitamin in a department of internal medicine may reveal paradoxically high …