Guidelines for the diagnosis and treatment of cobalamin and folate disorders

V Devalia, MS Hamilton, AM Molloy… - British journal of …, 2014 - Wiley Online Library
Summary of key recommendations The clinical picture is the most important factor in
assessing the significance of test results assessing cobalamin status because there is no …

Oral cyanocobalamin supplementation in older people with vitamin B12 deficiency: a dose-finding trial

SJPM Eussen, LC de Groot, R Clarke… - Archives of internal …, 2005 - jamanetwork.com
Background Supplementation with high doses of oral cobalamin is as effective as cobalamin
administered by intramuscular injection to correct plasma markers of vitamin B 12 deficiency …

Metabolic vitamin B12 deficiency: a missed opportunity to prevent dementia and stroke

JD Spence - Nutrition research, 2016 - Elsevier
The purpose of this narrative review is to highlight insights into the importance and
frequency of metabolic vitamin B12 (B12) deficiency, reasons why it is commonly missed …

[HTML][HTML] Cobalamin related parameters and disease patterns in patients with increased serum cobalamin levels

JFB Arendt, E Nexo - 2012 - journals.plos.org
Background Measurement of serum cobalamin levels is routinely used to diagnose
cobalamin deficiency. Surprisingly, approximately 15% of patients have high cobalamin …

Subclinical cobalamin deficiency

R Carmel - Current opinion in gastroenterology, 2012 - journals.lww.com
The story of SCCD, which is severalfold times more common in the elderly than clinical
cobalamin deficiency but also differs from it in arising only infrequently from severe …

Cobalamin and the nervous system

WS Beck - New England Journal of Medicine, 1988 - Mass Medical Soc
To the stalwart little band of investigators of vitamin B12—now more rationally termed
cobalamin—there is comfort in knowing that the stream of important scientific problems will …

[PDF][PDF] Carences en cobalamine: aspects neurologiques chez 27 patients Cobalamin deficiency: Neurological aspects in 27 cases

H El Otmani, F Moutaouakil, N Midafi… - revue …, 2009 - academia.edu
Methods.–This retrospective study included patients with neurological symptoms and
cobalamin (B12 vitamin) deficiency confirmed by laboratory tests collected over a period of …

11 Neurological complications of acquired cobalamin deficiency: clinical aspects

DG Savage, J Lindenbaum - Bailliere's clinical haematology, 1995 - Elsevier
Neuropsychiatric syndromes occur in about 40% of Cbl-deficient patients and are
characterized by progressive and variable damage to the spinal cord, peripheral nerves and …

Vitamin B12 deficiency

R Green, LH Allen, AL Bjørke-Monsen, A Brito… - Nature reviews Disease …, 2017 - nature.com
Abstract Vitamin B 12 (B12; also known as cobalamin) is a B vitamin that has an important
role in cellular metabolism, especially in DNA synthesis, methylation and mitochondrial …

[PDF][PDF] B12 deficiency: a look beyond pernicious anemia

S Affenberger, J Vidal‐Alaball, N Henoun, J Zimmer… - J Fam Pract, 2007 - researchgate.net
Further muddying the waters is the fact that B12 deficiency appears to be more common
among patients who have a variety of chronic neurologic conditions such as stroke …