Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)
CS Constantinescu, N Farooqi… - British journal of …, 2011 - Wiley Online Library
Experimental autoimmune encephalomyelitis (EAE) is the most commonly used
experimental model for the human inflammatory demyelinating disease, multiple sclerosis …
experimental model for the human inflammatory demyelinating disease, multiple sclerosis …
Neurodegeneration in autoimmune CNS inflammation
Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system, in which the myelin sheath has been considered to be the primary target for …
nervous system, in which the myelin sheath has been considered to be the primary target for …
Neuroinflammation, neurodegeneration and regeneration in multiple sclerosis: intercorrelated manifestations of the immune response
T Koudriavtseva, C Mainero - Neural regeneration research, 2016 - journals.lww.com
Multiple sclerosis (MS) is a chronic immune-mediated inflammatory-demyelinating disorder
of the central nervous system, with a strong neurodegenerative component. The question …
of the central nervous system, with a strong neurodegenerative component. The question …
Pathology of multiple sclerosis
M Kipp, P van der Valk, S Amor - CNS & Neurological …, 2012 - ingentaconnect.com
Pathological examination of the affected human tissue is key to understanding the possible
mechanisms operating in the disease. In multiple sclerosis (MS), studies of central nervous …
mechanisms operating in the disease. In multiple sclerosis (MS), studies of central nervous …
Cellular immunology of relapsing multiple sclerosis: interactions, checks, and balances
Novel insights from basic and translational studies are reshaping concepts of the
immunopathogenesis of multiple sclerosis and understanding of the different inflammatory …
immunopathogenesis of multiple sclerosis and understanding of the different inflammatory …
What drives disease in multiple sclerosis: inflammation or neurodegeneration?
H Lassmann - Clinical and Experimental Neuroimmunology, 2010 - Wiley Online Library
Multiple sclerosis (MS) is defined as a chronic inflammatory disease of the central nervous
system, which leads to focal inflammatory demyelinated lesions with secondary …
system, which leads to focal inflammatory demyelinated lesions with secondary …
Updates and advances in multiple sclerosis neurotherapeutics
The multiple sclerosis (MS) neurotherapeutic landscape is rapidly evolving. New disease-
modifying therapies (DMTs) with improved efficacy and safety, in addition to an expanding …
modifying therapies (DMTs) with improved efficacy and safety, in addition to an expanding …
Promoting remyelination in multiple sclerosis: current drugs and future prospects
D Kremer, P Küry, R Dutta - Multiple Sclerosis Journal, 2015 - journals.sagepub.com
Myelin destruction due to inflammatory oligodendrocyte cell damage or death in conjunction
with axonal degeneration are among the major histopathological hallmarks of multiple …
with axonal degeneration are among the major histopathological hallmarks of multiple …
Central nervous system remyelination: roles of glia and innate immune cells
In diseases such as multiple sclerosis (MS), inflammation can injure the myelin sheath that
surrounds axons, a process known as demyelination. The spontaneous regeneration of …
surrounds axons, a process known as demyelination. The spontaneous regeneration of …
Cell type-specific intralocus interactions reveal oligodendrocyte mechanisms in MS
Multiple sclerosis (MS) is an autoimmune disease characterized by attack on
oligodendrocytes within the central nervous system (CNS). Despite widespread use of …
oligodendrocytes within the central nervous system (CNS). Despite widespread use of …