Mitochondria maintain genome and translation machinery to synthesize a small subset of
subunits of the oxidative phosphorylation system. To build up functional enzymes, these …

Regulation of eukaryotic cytochrome oxidase assembly occurs at the level of Cox1
translation, its central mitochondria-encoded subunit. Translation of COX1 messenger RNA …

Mitochondrial ribosomes translate membrane integral core subunits of the oxidative
phosphorylation system encoded by mtDNA. These translation products associate with …

Mitochondrial cytochrome c oxidase (COX) is the primary site of cellular oxygen
consumption and is essential for aerobic energy generation in the form of ATP. Human COX …

Cytochrome c-oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain,
plays a key role in the regulation of aerobic production of energy. Biogenesis of eukaryotic …

The terminal enzyme of the respiratory chain, cytochrome c oxidase, consists of a
hydrophobic reaction center formed by three mitochondrially encoded subunits with which 9 …

Cytochrome c oxidase (COX) or complex IV of the mitochondrial respiratory chain plays a
fundamental role in energy production of aerobic cells. In humans, COX deficiency is the …

Publisher Summary This chapter discusses the cooperative interaction between
mitochondrial and nuclear genomes—cytochrome c oxidase assembly as a model. There …

Previous studies of yeast cytochrome oxidase (COX) biogenesis identified Cox1p, one of the
three mitochondrially encoded core subunits, in two high–molecular weight complexes …

The formation of the mature cytochrome c oxidase (complex IV) involves the association of
nuclear-and mitochondria-encoded subunits. The assembly of nuclear-encoded subunits …