Mitochondrial dysfunction is part of many pathological states in patients, such as sepsis or
stroke. Presently, the monitoring of mitochondrial function in patients is extremely rare, even …

Normal mitochondrial function is a critical factor in maintaining cellular homeostasis in
various organs of the body. Due to the involvement of mitochondrial dysfunction in many …

Normal mitochondrial function is a critical factor in maintaining cellular homeostasis in
various organs of the body. Due to the involvement of mitochondrial dysfunction in many …

In the process of energy production, mitochondrial networks are key elements to allow
metabolism of substrates into ATP. Many pathological conditions have been associated with …

Publisher Summary This chapter describes the origins of the study of nicotinamide adenine
dinucleotide (NADH) and fluoroprotein to show how they provide a window into the cell …

Herein, we report a rhodamine-based redox probe (MQR) to visualize cytosolic NADH in the
cellular milieu. Its high sensitivity and selectivity allowed it to track the alteration of the NADH …

Active changes in mitochondrial structure and organization facilitate cellular homeostasis.
Because aberrant mitochondrial dynamics are implicated in a variety of human diseases …

Mitochondrial redox states provide important information about energy-linked biological
processes and signaling events in tissues for various disease phenotypes including cancer …

The redox states of the NAD and NADP pyridine nucleotide pools play critical roles in
defining the activity of energy producing pathways, in driving oxidative stress and in …

Mitochondrial NADH fluorescence has been a useful tool in evaluating mitochondrial
energetics both in vitro and in vivo. Mitochondrial NADH fluorescence is enhanced several …