In recent years, fluorescent dyes have been frequently used for monitoring mitochondrial
membrane potential to evaluate mitochondrial viability and function. However, the …

The ratio of oxidized to reduced NAD (NAD+/NADH) sets intracellular redox balance and
antioxidant capacity. Intracellular NAD is compartmentalized and the mitochondrial …

The sensor for blood‐flow need with neural activity and exercise is not known. We tested the
hypothesis that accumulation of electrons in cytosolic free nicotinamide adenine …

Sepsis represents a deranged and exaggerated systemic inflammatory response to infection
and is associated with vascular and metabolic abnormalities that trigger systemic organic …

The current mainstream view of organ failure induced by sepsis revolves around
inflammation and loss of vascular control. However, there has been a resurgence in interest …

Significance: Hypoxic-ischemic events due to intrapartum complications represent the
second cause of neonatal mortality and initiate an acute brain disorder known as hypoxic …

Renal ischemia and subsequent reperfusion lead to changes in the regulation of hydrogen
ions across the mitochondrial membrane. This study was designed to monitor pH changes in …

Nicotinamide adenine dinucleotide (NAD+/NADH) along with its phosphorylated form
(NADP+/NADPH) are two molecules ubiquitously present in all organisms, and they play key …

Nitric oxide (NO) is known to inhibit reversibly mitochondrial respiration. This study aimed at
clarifying whether low level illumination at specific wavelengths recovers mitochondrial …

Mitochondrial disorders represent a large collection of rare syndromes that are difficult to
manage both because we do not fully understand biochemical pathogenesis and because …