Fabrication and optimization of novel glipizide sustained release matrices for solubility and dissolution enhancement by solid dispersion through hydrophillic carriers
MA Shende, PV Fiske - Journal of Drug Delivery and Therapeutics, 2017 - jddtonline.info
The present research work was to improve the dissolution rate of glipizide which belongs to
BCS II drug by enhancing its aqueous solubility using different hydrophilic carriers like PEG …
BCS II drug by enhancing its aqueous solubility using different hydrophilic carriers like PEG …
[PDF][PDF] Formulation, evaluation and optimization of solid dispersion of Glipizide using face centered central composite design
The aim of this study was to increase the solubility and dissolution of glipizide-a practically
water insoluble drug. To achieve complete drug release, various batches of solid dispersion …
water insoluble drug. To achieve complete drug release, various batches of solid dispersion …
Design and evaluation of hydrophilic matrix system for pH-independent sustained release of weakly acidic poorly soluble drug
J Huang, H Lin, B Peng, Q Huang, F Shuai, Y Xie - AAPS PharmSciTech, 2018 - Springer
The aim of this research was to design and evaluate a hydrophilic matrix system for
sustained release of glipizide, a weakly acidic poor soluble drug. A combination of inclusion …
sustained release of glipizide, a weakly acidic poor soluble drug. A combination of inclusion …
[HTML][HTML] Formulation and characterization of glipizide solid dosage form with enhanced solubility
Glipizide, a poor water-soluble drug belongs to BCS class II. The proposed work aimed to
enhance the solubility of glipizide by preparing solid dispersions, using polyvinyl pyrrolidone …
enhance the solubility of glipizide by preparing solid dispersions, using polyvinyl pyrrolidone …
Development of a controlled release low dose class II drug-Glipizide
S Jamzad, R Fassihi - International journal of pharmaceutics, 2006 - Elsevier
The purpose of this study was to develop a new monolithic matrix system to completely
deliver glipizide, a Biopharmaceutics Classification System (BCS) Class II drug in a zero …
deliver glipizide, a Biopharmaceutics Classification System (BCS) Class II drug in a zero …
Solid carriers for improved solubility of glipizide in osmotically controlled oral drug delivery system
A Mehramizi, B Alijani, M Pourfarzib… - Drug development …, 2007 - Taylor & Francis
The purpose of this study was to increase the solubility of glipizide (gli) by solid dispersions
SDs technique with polyvinylpyrrolidone (PVP) in aqueous media. The gli–PVP solid …
SDs technique with polyvinylpyrrolidone (PVP) in aqueous media. The gli–PVP solid …
[PDF][PDF] Research Paper Preparation and Evaluation of Glipizide Tablets Containing both Enhanced and Sustained Release Solid Dispersions
AM Aly, AS Ali - Int. J Pharm. Sci. Nanotech, 2010 - researchgate.net
Glipizide (GZ) is an oral blood-glucose-lowering drug of the sulfonylurea class characterized
by its poor aqueous solubility. Aiming for the production of GZ tablets with rapid onset of …
by its poor aqueous solubility. Aiming for the production of GZ tablets with rapid onset of …
[PDF][PDF] Formulation and evaluation of solid dispersions of glipizide for dissolution rate enhancement
MR Shivalingam, T Jyothibasu, YVK Reddy… - Int. J. Pharma. Res …, 2011 - academia.edu
Glipizide is a class-II antidiabetic drug which is purely insoluble in water. Since only
dissolved drug can pass the gastro intestinal membrane, proper solubility of the drug is …
dissolved drug can pass the gastro intestinal membrane, proper solubility of the drug is …
Development and optimization of multi-unit solid dispersion systems of poorly water soluble drug
Glipizide (GPZ) and GPZ-HPC solid dispersion (SD) pellets were developed and
characterized for drug release mechanisms from a multi-unit erosion matrix system for …
characterized for drug release mechanisms from a multi-unit erosion matrix system for …
[PDF][PDF] Formulation and evaluation of glipizide sustain release matrix tablets
S Giri, S Velmurugan, S Chowdary - International Journal of …, 2013 - scholar.archive.org
ABSTRACT Objective: The Glipizide matrix tablet were prepared using different hydrophilic
polymers (HPMC different grades and sodium CMC) in various proportions as release …
polymers (HPMC different grades and sodium CMC) in various proportions as release …