Alzheimer Disease—Link With Major Depressive Disorder and Efficacy of Antidepressants in Modifying its Trajectory

N Fakih, M Fakhoury - Journal of Psychiatric Practice®, 2024 - journals.lww.com
Alzheimer disease (AD) is a devastating neurodegenerative disorder that affects millions of
individuals worldwide, with no effective cure. The main symptoms include learning and …

What is the association between depression and Alzheimer's disease?

N Tsuno, A Homma - Expert review of neurotherapeutics, 2009 - Taylor & Francis
Depression and dementia, in particular Alzheimer's disease (AD), are critically important
issues in the mental health of old age. Both conditions apparently reduce quality of life and …

[HTML][HTML] Pharmacological treatment of depression in Alzheimer's disease: a challenging task

T Cassano, S Calcagnini, A Carbone… - Frontiers in …, 2019 - frontiersin.org
Besides the memory impairment, Alzheimer's disease (AD) is often complicated by
neuropsychiatric symptoms also known as behavioral and psychological symptoms of …

[图书][B] Depression in Alzheimer's disease: biomarkers and treatment

D Enache - 2015 - search.proquest.com
Depression and Alzheimer's disease (AD) are among the most common clinical diagnosis in
older people. The relation between depression and AD is complex: depression has been …

[HTML][HTML] The Interface between Depression and Alzheimer's Disease. A Comprehensive Approach

PJ Modrego, LD de Cerio, A Lobo - Annals of Indian Academy of …, 2023 - journals.lww.com
Depression and Alzheimer's disease (AD) are frequent interacting diseases in the elderly
with a negative impact on the quality of life of patients and caregivers. Late-life depression …

Impact of antidepressant use on the trajectory of Alzheimer's disease: evidence, mechanisms, and therapeutic implications

R Khoury, GT Grossberg - CNS drugs, 2019 - Springer
The relationship between antidepressants and Alzheimer's disease (AD) is very complex,
and the literature is mixed regarding the effect of these medications on the trajectory of the …

The challenge of antidepressant therapeutics in Alzheimer's disease

M Lozupone, M La Montagna, F D'Urso… - Reviews on New Drug …, 2020 - Springer
The link between depression and Alzheimer's disease (AD) is controversial, because it is not
clear if depression is an independent risk factor for the disease or a prodromal symptom in …

[HTML][HTML] Alzheimer's Disease From a Psychiatric Perspective: Towards New Therapeutic Guidelines?

M Fakhoury, F Piras, N Banaj - Frontiers in Psychiatry, 2021 - frontiersin.org
Alzheimer's disease (AD) is a debilitating neurodegenerative disorder and the most common
cause of dementia (1). It was first described in 1906 by the German physician, Alois …

Depression in Alzheimer's disease: epidemiology, mechanisms, and treatment

YY Huang, YH Gan, L Yang, W Cheng, JT Yu - Biological Psychiatry, 2023 - Elsevier
Depression and Alzheimer's disease (AD) are substantial public health concerns. In the past
decades, a link between two disease entities has received extensive acknowledgment, yet …

Depression in Alzheimer's disease: epidemiology, mechanisms, and management

S Chi, JT Yu, MS Tan, L Tan - Journal of Alzheimer's disease, 2014 - content.iospress.com
Depression occurs with a high prevalence of up to 50% in patients with Alzheimer's disease
(AD) and increases the caregivers' burden. Depression symptoms can precede clinical …