Ventilation with enhanced fractions of O 2 (hyperoxia) is a common and necessary treatment
for hypoxemia in patients with lung failure, but prolonged exposure to hyperoxia causes lung …

Recently, we demonstrated the utility of optical fluorometry to detect a change in the redox
status of mitochondrial autofluorescent coenzymes nicotinamide adenine dinucleotide …

We have imaged mitochondrial oxidation–reduction states by taking a ratio of mitochondrial
fluorophores: NADH (reduced nicotinamide adenine dinucleotide) to Fp (oxidized …

We designed a fiber-optic-based optoelectronic fluorometer to measure emitted
fluorescence from the auto-fluorescent electron carriers NADH and FAD of the mitochondrial …

Oxidation of substrates to generate ATP in mitochondria is mediated by redox reactions of
NADH and FADH2. Cardiac ischemia and reperfusion (IR) injury compromises …

Whole thoracic irradiation (WTI) is known to cause deterioration in cardiac function. Whether
irradiation predisposes the heart to further ischemia and reperfusion (IR) injury is not well …

The fluorescence properties of reduced nicotinamide adenine dinucleotide (NADH) and
oxidized flavoproteins (Fp) such as flavin adenine dinucleotide (FAD) in the respiratory …

The heart requires continuous ATP availability that is generated in the mitochondria.
Although studies using the cell culture and perfused organ models have been carried out to …

The fluorescence properties of reduced nicotinamide adenine dinucleotide (NADH) and
oxidized flavoproteins (Fp) including flavin adenine dinucleotide (FAD) in the respiratory …

Reactive oxygen species (ROS) have been implicated in the pathogenesis of many acute
and chronic pulmonary disorders such as acute lung injury (ALI) in adults and …