Hypersensitivity of cardiac β-adrenergic receptors after neonatal treatment of rats with 6-hydroxydopa

Y Nomura, H Kajiyama, T Segawa - European Journal of Pharmacology, 1980 - Elsevier
The cardiac β-adrenergic response to noradrenaline (NA) was investigated in the rat
neonatally sc treated with 6-hydroxydopa (6-OHDOPA, 75 mg/kg, 0, 2 and 4 days after birth) …

The increase of cardiac β1-subtype of β-adrenergic receptors in adult rats following neonatal 6-hydroxydopa treatment

H Kajiyama, K Obara, Y Nomura, T Segawa - European Journal of …, 1982 - Elsevier
An analysis of Hofstee plots of specific [3 H] dihydroalprenolol ([3 H] DHA) binding in the
presence of various concentrations of practolol showed that KD and B max in β 1-subtype …

Effect of neonatal 6-hydroxydopamine treatment on α1-and α2-adrenoceptors in rat cerebral cortex

JP Dausse, KH Le Quan-Bui… - Journal of Cardiovascular …, 1982 - journals.lww.com
Neonatal 6-hydroxydopamine (6-OHDA) treatment was used to destroy the noradrenergic
nerve endings in rat cerebral cortex and thus give some insight into the development and …

Alterations in β-adrenoceptor number and catecholamine content of chick atria after reversible sympathetic denervation with 6-hydroxydopamine

K Williams, PG Strange, T Bennett - Naunyn-Schmiedeberg's archives of …, 1987 - Springer
The characteristics of [3 H]-dihydroalprenolol (DHA) binding were determined in atria from
untreated chicks.[3 H]-DHA binding to atrium homogenates was rapid (k 1= 8.52× 10 8 1 …

Identification of β-Adrenergic Receptors Using [3H] Dihydroalprenolol in Fetal Sheep Heart: Direct Evidence of Qualitative Similarity to the Receptors in Adult Sheep …

JB Cheng, A Goldfien, LE Cornett, JM Roberts - Pediatric Research, 1981 - nature.com
The fetal sheep heart responds to β-adrenergic stimuli; however, in vivo studies show the
response of the fetal heart is less than that of the adult heart. We used [3 H] …

Alterations in cardiac autonomic receptors following 6-hydroxydopamine treatment in rats

S YAMADA, HI YAMAMURA, WR ROESKE - Molecular Pharmacology, 1980 - ASPET
To characterize the regional changes in β-adrenergic and muscarinic cholinergic receptors
in rat hearts following 6-hydroxydopamine (6-OHDA) treatment, receptor binding assays …

Ontogeny of Myocardial α (1)-Adrenergic Receptor in the Rat

A Noguchi, JA Whitsett, L Dickman - Developmental Pharmacology and …, 1981 - karger.com
The ai-adrenergic specific radioligand [3H]-prazosin and the ß-adrenergic radioligand (-)-
[3H]-dihydroalprenolol [(-)-[3H]-DHA] were used to describe the postnatal ontogeny of α (1) …

Increased beta 2-adrenoreceptor density in heart, kidney and lung of spontaneously hypertensive rats.

MC Michel, XL Wang, E Schlicker… - Journal of autonomic …, 1987 - europepmc.org
The development of beta-adrenoreceptor density and beta 1-and beta 2-adrenoreceptor
distribution has been investigated in heart, kidney and lung of spontaneously hypertensive …

Enhanced noradrenaline response in cardiomyopathic hamsters: possible relation to changes in adrenoceptors studied by radioligand binding

JS KARLINER, C ALABASTER… - Cardiovascular …, 1981 - academic.oup.com
To assess the possible relation between catecholamine responses and adrenoceptor affinity
and density, we compared the effect of noradrenaline, isoprenaline and ouabain on right …

Ontogeny of mammalian myocardial β-adrenergic receptors

FCM Chen, HI Yamamura, WR Roeske - European Journal of …, 1979 - Elsevier
Little information is available regarding the ontogenesis of the mammalian cardiac β-
receptor and its relationship to physiological responses. In this study, β-adrenergic receptors …