There is now considerable evidence for an increased oxidant burden in patients with chronic
obstructive pulmonary disease (COPD). Oxidative stress is a critical feature in the …

There is now considerable evidence for an increased oxidant burden in smokers,
particularly in those smokers who develop chronic obstructive pulmonary disease (COPD) …

AM J RESPIR CRIT CARE MED 1999; 160: S58− S65. There is now increasing evidence
that an oxidant/antioxidant imbalance, in favor of oxidants, occurs in chronic obstructive …

An imbalance between oxidants and antioxidants is considered to play a role in the
pathogenesis of chronic obstructive pulmonary disease (COPD). There is considerable …

There is a marked increase in oxidative stress in the lungs of patients with COPD, as
measured by increased exhaled 8-isoprostane, ethane, and hydrogen peroxide in the …

Markers of oxidative stress are increased in chronic obstructive pulmonary disease (COPD)
and reactive oxygen species (ROS) are able to alter biological molecules, signaling …

There is overwhelming evidence that oxidative stress and oxidative damage play a pivotal
role in the pathogenesis of chronic obstructive pulmonary disease (COPD)(1-3). The …

Oxidative stress results from an oxidant/antioxidant imbalance, an excess of oxidants and/or
a depletion of antioxidants. Oxidative stress is thought to play an important role in the …

Chronic inflammation and oxidative stress are important features in the pathogenesis of
COPD. The increased oxidative stress in patients with COPD is the result of an increased …

The respiratory system is continuously exposed to endogenous and exogenous oxidants.
Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation of …