Background: Antidepressant efficacy may be compromised by early discontinuation of
treatment secondary to common, treatment-emergent side effects, including nausea …

Introduction The UK's current National Institute for Health and Care Excellence and the
American Psychiatric Association's depression guidelines state that withdrawal reactions …

A randomized, double‐blind, parallel‐group, 6‐week study was undertaken to compare the
efficacy and tolerability of once or twice daily administration of the selective serotonin …

AIMS AND METHOD: Withdrawal symptoms are associated with cessation of all
antidepressants but particularly paroxetine and venlafaxine. We aimed to examine rates of …

TO THE EDITOR: In the December 2018 issue of the Journal, Jha and colleagues (1) claim
that antidepressant withdrawal typically resolves spontaneously over 2–3 weeks. They offer …

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Understanding the particular pharmacology of different antidepressant drugs can help
explain their adverse effects when they are discontinued. For all antidepressant drugs …

To compare the safety and efficacy of paroxetine (n= 167) and placebo (n= 169), data from 4
centres using the same protocol were pooled. A double‐blind parallel group design was …

Background Antidepressant drugs are important in the treatment of major depression. The
use of antidepressants in general and more specifically selective serotonin reuptake …

This article reanalyses and reviews data from the two published randomized clinical trials
comparing escitalopram and venlafaxine XR in the treatment of patients with major …