[PDF][PDF] Self emulsified drug delivery system for the enhancement of oral bioavailability of poorly water soluble drugs

M Bhupinder, G Roy, B Bajwa, K Sandeep - International journal of …, 2013 - Citeseer
Oral route still remains the favorite route of drug administration in many diseases and till
today it is the first way investigated in the development of new dosage forms. But the major …

Insights into novel excipients of self-emulsifying drug delivery systems and their significance: an updated review

ER Rani, GV Radha - Critical Reviews™ in Therapeutic Drug …, 2021 - dl.begellhouse.com
Self-emulsifying drug delivery system (SEDDS), a category of lipid-based technology, has
gained interest in the recent years for enhancement of solubility and bioavailability of poorly …

Development of solid self-emulsifying drug delivery systems: preparation techniques and dosage forms

B Tang, G Cheng, JC Gu, CH Xu - Drug discovery today, 2008 - Elsevier
Approximately 40% of new chemical entities exhibit poor aqueous solubility and present a
major challenge to modern drug delivery system, because of their low bioavailability. Self …

[PDF][PDF] Solid self-emulsifying drug delivery system: Preparation techniques and dosage forms

MP Wagh, PK Singh, CS Chaudhari… - International journal of …, 2014 - Citeseer
Drugs are most often administered by the oral route. However, more than 40% of new
chemical entities exhibit poor aqueous solubility, resulting in unsatisfactory oral drug …

[PDF][PDF] Self-emulsifying drug delivery systems (SEDDS): An update from formulation development to therapeutic strategies

AK Mahapatra, PN Murthy, B Swadeep… - Int J PharmTech …, 2014 - researchgate.net
Improving oral bioavailability of low poorly water soluble drugs using self emulsifying drug
delivery systems (SEDDS) possess significant potential. Oral bioavailability of hydrophobic …

A rundown through various methods used in the formulation of solid self-emulsifying drug delivery systems (S-SEDDS)

SRD Almeida, VK Tippavajhala - Aaps Pharmscitech, 2019 - Springer
The most common route of the drug administration is oral route despite the fact that most
drugs have low oral aqueous solubility and bioavailability especially for BCS class II and …

Overview of solidification techniques for self-emulsifying drug delivery systems from industrial perspective

J Mandić, AZ Pobirk, F Vrečer, M Gašperlin - International journal of …, 2017 - Elsevier
Self-emulsifying drug delivery systems (SEDDS) are lipid formulations that improve solubility
and oral bioavailability of the incorporated drug with poor biopharmaceutical properties. As …

[PDF][PDF] Novel approaches for development and characterization of SMEDDS

U Deokate, N Shinde, U Bhingare - Int J Curr Pharm Res, 2013 - academia.edu
As development of modern drug discovery technique, there has been steady increase in
number of new pharmacologicaly active lipophilic compounds that are poorly water soluble …

A new self-emulsifying drug delivery system (SEDDS) for poorly soluble drugs: characterization, dissolution, in vitro digestion and incorporation into solid pellets

A Abdalla, S Klein, K Mäder - European journal of pharmaceutical sciences, 2008 - Elsevier
The aim of the current study was the development of a new pellet based self-emulsifying
(SE) drug delivery system for the oral delivery of poorly soluble drugs. Furthermore, we …

Solid self emulsifying drug delivery system: Superior mode for oral delivery of hydrophobic cargos

I Maji, S Mahajan, A Sriram, P Medtiya… - Journal of Controlled …, 2021 - Elsevier
A significant proportion of recently approved drug molecules possess poor aqueous
solubility which further restrains their desired bioavailability. Poor aqueous solubility of these …